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Inhibition of P. aeruginosa c-di-GMP phosphodiesterase RocR and swarming motility by a benzoisothiazolinone derivative

Various important cellular processes in bacteria are controlled by c-di-GMP, such as motility, biofilm formation and virulence factors production. C-di-GMP is synthesized from two molecules of GTP by diguanylate cyclases (DGCs) and its actions are terminated by EAL or HD-GYP domain phosphodiesterase...

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Detalles Bibliográficos
Autores principales:	Zheng, Yue, Tsuji, Genichiro, Opoku-Temeng, Clement, Sintim, Herman O.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Royal Society of Chemistry 2016
Materias:	Chemistry
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6024209/ https://www.ncbi.nlm.nih.gov/pubmed/30034764 http://dx.doi.org/10.1039/c6sc02103d

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