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Dietary Nutrients and Bioactive Substances Modulate Heat Shock Protein (HSP) Expression: A Review

Interest in the heat shock proteins (HSPs), as a natural physiological toolkit of living organisms, has ranged from their chaperone function in nascent proteins to the remedial role following cell stress. As part of the defence system, HSPs guarantee cell tolerance against a variety of stressors, in...

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Autores principales: Moura, Carolina Soares, Lollo, Pablo Christiano Barboza, Morato, Priscila Neder, Amaya-Farfan, Jaime
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6024325/
https://www.ncbi.nlm.nih.gov/pubmed/29843396
http://dx.doi.org/10.3390/nu10060683
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author Moura, Carolina Soares
Lollo, Pablo Christiano Barboza
Morato, Priscila Neder
Amaya-Farfan, Jaime
author_facet Moura, Carolina Soares
Lollo, Pablo Christiano Barboza
Morato, Priscila Neder
Amaya-Farfan, Jaime
author_sort Moura, Carolina Soares
collection PubMed
description Interest in the heat shock proteins (HSPs), as a natural physiological toolkit of living organisms, has ranged from their chaperone function in nascent proteins to the remedial role following cell stress. As part of the defence system, HSPs guarantee cell tolerance against a variety of stressors, including exercise, oxidative stress, hyper and hypothermia, hyper and hypoxia and improper diets. For the past couple of decades, research on functional foods has revealed a number of substances likely to trigger cell protection through mechanisms that involve the induction of HSP expression. This review will summarize the occurrence of the most easily inducible HSPs and describe the effects of dietary proteins, peptides, amino acids, probiotics, high-fat diets and other food-derived substances reported to induce HSP response in animals and humans studies. Future research may clarify the mechanisms and explore the usefulness of this natural alternative of defense and the modulating mechanism of each substance.
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spelling pubmed-60243252018-07-08 Dietary Nutrients and Bioactive Substances Modulate Heat Shock Protein (HSP) Expression: A Review Moura, Carolina Soares Lollo, Pablo Christiano Barboza Morato, Priscila Neder Amaya-Farfan, Jaime Nutrients Review Interest in the heat shock proteins (HSPs), as a natural physiological toolkit of living organisms, has ranged from their chaperone function in nascent proteins to the remedial role following cell stress. As part of the defence system, HSPs guarantee cell tolerance against a variety of stressors, including exercise, oxidative stress, hyper and hypothermia, hyper and hypoxia and improper diets. For the past couple of decades, research on functional foods has revealed a number of substances likely to trigger cell protection through mechanisms that involve the induction of HSP expression. This review will summarize the occurrence of the most easily inducible HSPs and describe the effects of dietary proteins, peptides, amino acids, probiotics, high-fat diets and other food-derived substances reported to induce HSP response in animals and humans studies. Future research may clarify the mechanisms and explore the usefulness of this natural alternative of defense and the modulating mechanism of each substance. MDPI 2018-05-28 /pmc/articles/PMC6024325/ /pubmed/29843396 http://dx.doi.org/10.3390/nu10060683 Text en © 2018 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Moura, Carolina Soares
Lollo, Pablo Christiano Barboza
Morato, Priscila Neder
Amaya-Farfan, Jaime
Dietary Nutrients and Bioactive Substances Modulate Heat Shock Protein (HSP) Expression: A Review
title Dietary Nutrients and Bioactive Substances Modulate Heat Shock Protein (HSP) Expression: A Review
title_full Dietary Nutrients and Bioactive Substances Modulate Heat Shock Protein (HSP) Expression: A Review
title_fullStr Dietary Nutrients and Bioactive Substances Modulate Heat Shock Protein (HSP) Expression: A Review
title_full_unstemmed Dietary Nutrients and Bioactive Substances Modulate Heat Shock Protein (HSP) Expression: A Review
title_short Dietary Nutrients and Bioactive Substances Modulate Heat Shock Protein (HSP) Expression: A Review
title_sort dietary nutrients and bioactive substances modulate heat shock protein (hsp) expression: a review
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6024325/
https://www.ncbi.nlm.nih.gov/pubmed/29843396
http://dx.doi.org/10.3390/nu10060683
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