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Using Fragment-Based Approaches to Discover New Antibiotics
Fragment-based lead discovery has emerged over the past two decades as a successful approach to generate novel lead candidates in drug discovery programs. The two main advantages over conventional high-throughput screening (HTS) are more efficient sampling of chemical space and tighter control over...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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SAGE Publications
2018
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6024353/ https://www.ncbi.nlm.nih.gov/pubmed/29923463 http://dx.doi.org/10.1177/2472555218773034 |