An inhibitor of spleen tyrosine kinase suppresses experimental crescentic glomerulonephritis

Non-selective inhibitors of spleen tyrosine kinase (SYK) efficiently suppress disease in T cell-dependent models of crescentic glomerulonephritis. However, the therapeutic potential of selective SYK inhibitors in this disease has not been established. In addition, we lack knowledge regarding SYK exp...

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Detalles Bibliográficos
Autores principales: Han, Yingjie, Ma, Frank Y, Di Paolo, Julie, Nikolic-Paterson, David J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2018
Materias:
Original Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6024518/
https://www.ncbi.nlm.nih.gov/pubmed/29923438
http://dx.doi.org/10.1177/2058738418783404

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