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Engineering of Botulinum Neurotoxins for Biomedical Applications
Botulinum neurotoxins (BoNTs) have been used as therapeutic agents in the clinical treatment of a wide array of neuromuscular and autonomic neuronal transmission disorders. These toxins contain three functional domains that mediate highly specific neuronal cell binding, internalization and cytosolic...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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MDPI
2018
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6024800/ https://www.ncbi.nlm.nih.gov/pubmed/29882791 http://dx.doi.org/10.3390/toxins10060231 |