Cargando…

Inhibition of Hepatitis E Virus Spread by the Natural Compound Silvestrol

Every year, there are about 20 Mio hepatitis E virus (HEV) infections and 60,000 deaths that are associated with HEV worldwide. At the present, there exists no specific therapy for HEV. The natural compound silvestrol has a potent antiviral effect against the (−)-strand RNA-virus Ebola virus, and al...

Descripción completa

Detalles Bibliográficos
Autores principales:	Glitscher, Mirco, Himmelsbach, Kiyoshi, Woytinek, Kathrin, Johne, Reimar, Reuter, Andreas, Spiric, Jelena, Schwaben, Luisa, Grünweller, Arnold, Hildt, Eberhard
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6024817/ https://www.ncbi.nlm.nih.gov/pubmed/29865243 http://dx.doi.org/10.3390/v10060301

Ejemplares similares

Inhibition of Zika Virus Replication by Silvestrol
por: Elgner, Fabian, et al.
Publicado: (2018)

Comparison of broad-spectrum antiviral activities of the synthetic rocaglate CR-31-B (−) and the eIF4A-inhibitor Silvestrol
por: Müller, Christin, et al.
Publicado: (2020)

Natural antiviral compound silvestrol modulates human monocyte‐derived macrophages and dendritic cells
por: Blum, Leonard, et al.
Publicado: (2020)

Silvestrol Inhibits Chikungunya Virus Replication
por: Henss, Lisa, et al.
Publicado: (2018)

In Vitro Safety, Off-Target and Bioavailability Profile of the Antiviral Compound Silvestrol
por: Schiffmann, Susanne, et al.
Publicado: (2022)

Endosomal Cholesterol in Viral Infections – A Common Denominator?
por: Glitscher, Mirco, et al.
Publicado: (2021)

Targeting Cholesterol Metabolism as Efficient Antiviral Strategy Against the Hepatitis E Virus
por: Glitscher, Mirco, et al.
Publicado: (2021)

Broad-spectrum antiviral activity of the eIF4A inhibitor silvestrol against corona- and picornaviruses
por: Müller, Christin, et al.
Publicado: (2018)

Hepatitis B und C: Mechanismen der virusinduzierten Leberpathogenese und Tumorentstehung
por: Glitscher, Mirco, et al.
Publicado: (2022)

Die Virushepatitiden A bis E: Prävalenz, Erregermerkmale und Pathogenese
por: Bender, Daniela, et al.
Publicado: (2021)

Relevance of HBx for Hepatitis B Virus-Associated Pathogenesis
por: Schollmeier, Anja, et al.
Publicado: (2023)

Identification of various cell culture models for the study of Zika virus
por: Himmelsbach, Kiyoshi, et al.
Publicado: (2018)

The natural compound silvestrol inhibits hepatitis E virus (HEV) replication in vitro and in vivo
por: Todt, Daniel, et al.
Publicado: (2018)

Life cycle and morphogenesis of the hepatitis E virus
por: Himmelsbach, Kiyoshi, et al.
Publicado: (2018)

Targeting of CXCR4 by the Naturally Occurring CXCR4 Antagonist EPI-X4 in Waldenström’s Macroglobulinemia
por: Kaiser, Lisa Marie, et al.
Publicado: (2021)

Therapeutic Potential of the Translation Inhibitor Silvestrol in Hepatocellular Cancer
por: Kogure, Takayuki, et al.
Publicado: (2013)

Bafilomycin A1 and U18666A Efficiently Impair ZIKV Infection
por: Sabino, Catarina, et al.
Publicado: (2019)

Antitumor Activity and Mechanism of Action of the Cyclopenta[b]benzofuran, Silvestrol
por: Cencic, Regina, et al.
Publicado: (2009)

Silvestrol induces early autophagy and apoptosis in human melanoma cells
por: Chen, Wei-Lun, et al.
Publicado: (2016)

In silico study on the Hepatitis E virus RNA Helicase and its inhibition by silvestrol, rocaglamide and other flavagline compounds
por: Pedroni, Lorenzo, et al.
Publicado: (2022)

Presence of Intact Hepatitis B Virions in Exosomes
por: Wu, Qingyan, et al.
Publicado: (2022)

Quadruple mutation GCAC1809-1812TTCT acts as a biomarker in healthy European HBV carriers
por: Peiffer, Kai-Henrik, et al.
Publicado: (2020)

Cell-permeable capsids as universal antigen carrier for the induction of an antigen-specific CD8(+) T-cell response
por: Akhras, Sami, et al.
Publicado: (2017)

Inhibition of nasopharyngeal carcinoma cell proliferation and synergism of cisplatin with silvestrol and episilvestrol isolated from Aglaia stellatopilosa
por: DAKER, MAELINDA, et al.
Publicado: (2016)

Quality Control of Biomedicinal Allergen Products – Highly Complex Isoallergen Composition Challenges Standard MS Database Search and Requires Manual Data Analyses
por: Spiric, Jelena, et al.
Publicado: (2015)

The eIF4A inhibitor silvestrol sensitizes T-47D ductal breast carcinoma cells to external-beam radiotherapy
por: Webb, Thomas E., et al.
Publicado: (2020)

Development of a novel method for identification and quantification of birch pollen allergens in parallel
por: Spiric, Jelena, et al.
Publicado: (2014)

Stability of Hepatitis E Virus After Drying on Different Surfaces
por: Wolff, Alexander, et al.
Publicado: (2022)

The Translated Amino Acid Sequence of an Insertion in the Hepatitis E Virus Strain 47832c Genome, But Not the RNA Sequence, Is Essential for Efficient Cell Culture Replication
por: Scholz, Johannes, et al.
Publicado: (2021)

Rotaviruses in Wild Ungulates from Germany, 2019–2022
por: Althof, Nadine, et al.
Publicado: (2023)

Silvestrol exhibits significant in vivo and in vitro antileukemic activities and inhibits FLT3 and miR-155 expressions in acute myeloid leukemia
por: Alachkar, Houda, et al.
Publicado: (2013)

Coronaviruses are stable on glass, but are eliminated by manual dishwashing procedures
por: Schilling-Loeffler, Katja, et al.
Publicado: (2022)

Hepatitis E Virus in Wild Boars and Spillover Infection in Red and Roe Deer, Germany, 2013–2015
por: Anheyer-Behmenburg, Helena E., et al.
Publicado: (2017)

Virale Hepatitis – ein versteckter Killer
por: Hildt, Eberhard
Publicado: (2022)

Übersicht über die in der EU zugelassenen COVID-19-Impfstoffe – von der Technologie über die klinische Prüfung zur Zulassung
por: Hildt, Eberhard
Publicado: (2022)

The translation inhibitor silvestrol exhibits direct anti-tumor activity while preserving innate and adaptive immunity against EBV-driven lymphoproliferative disease
por: Patton, John T., et al.
Publicado: (2014)

Thermal stability of hepatitis E virus assessed by a molecular biological approach
por: Schielke, Anika, et al.
Publicado: (2011)

Recent knowledge on hepatitis E virus in Suidae reservoirs and transmission routes to human
por: Pavio, Nicole, et al.
Publicado: (2017)

Effect of Sodium Chloride, Sodium Nitrite and Sodium Nitrate on the Infectivity of Hepatitis E Virus
por: Wolff, Alexander, et al.
Publicado: (2020)

Das Hepatitis-E-Virus – ein zoonotisches Virus: Verbreitung, Übertragungswege und Bedeutung für die Lebensmittelsicherheit
por: Johne, Reimar, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_445m4gtr6k2kqh6nuddfoqlv1i