Cargando…

Effects of Glucose with Casein Peptide Supplementation on Post-Exercise Muscle Glycogen Resynthesis in C57BL/6J Mice

Numerous studies have reported that post-exercise ingestion of carbohydrates with protein supplementation can enhance glycogen recovery. However, few reports have focused on the degrees of degradation of the ingested proteins due to post-exercise glycogen resynthesis. Accordingly, the aim of this st...

Descripción completa

Detalles Bibliográficos
Autores principales: Matsunaga, Yutaka, Sakata, Yasuyuki, Yago, Takumi, Nakamura, Hirohiko, Shimizu, Takashi, Takeda, Yasuhiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6024860/
https://www.ncbi.nlm.nih.gov/pubmed/29891805
http://dx.doi.org/10.3390/nu10060753
_version_ 1783336150193143808
author Matsunaga, Yutaka
Sakata, Yasuyuki
Yago, Takumi
Nakamura, Hirohiko
Shimizu, Takashi
Takeda, Yasuhiro
author_facet Matsunaga, Yutaka
Sakata, Yasuyuki
Yago, Takumi
Nakamura, Hirohiko
Shimizu, Takashi
Takeda, Yasuhiro
author_sort Matsunaga, Yutaka
collection PubMed
description Numerous studies have reported that post-exercise ingestion of carbohydrates with protein supplementation can enhance glycogen recovery. However, few reports have focused on the degrees of degradation of the ingested proteins due to post-exercise glycogen resynthesis. Accordingly, the aim of this study was to clarify the effects of differences in protein degradation on muscle glycogen recovery. Male seven-week-old C57BL/6J mice performed a single bout of 60-min treadmill running exercise and were then orally administered glucose (Glu; 1.5 mg/g body weight (BW)), glucose with casein peptide (Glu + Pep; 1.5 + 0.5 mg/g BW) or its constituent amino acid mixture (Glu + AA; 1.5 + 0.5 mg/g BW). At 120 min after supplementation, the soleus muscle glycogen content in the Glu and Glu + AA groups was significantly higher than that immediately after exercise; however, no such difference was observed in the Glu + Pep group. Blood substrate concentration and insulin signaling did not differ among the three groups. Furthermore, energy expenditure during the recovery period in the Glu + Pep group was significantly higher than that in the Glu and Glu + AA groups. These findings suggest that post-exercise co-ingestion of glucose and casein peptide might delay glycogen resynthesis, at least in part through increased energy expenditure caused by casein peptide ingestion.
format Online
Article
Text
id pubmed-6024860
institution National Center for Biotechnology Information
language English
publishDate 2018
publisher MDPI
record_format MEDLINE/PubMed
spelling pubmed-60248602018-07-08 Effects of Glucose with Casein Peptide Supplementation on Post-Exercise Muscle Glycogen Resynthesis in C57BL/6J Mice Matsunaga, Yutaka Sakata, Yasuyuki Yago, Takumi Nakamura, Hirohiko Shimizu, Takashi Takeda, Yasuhiro Nutrients Article Numerous studies have reported that post-exercise ingestion of carbohydrates with protein supplementation can enhance glycogen recovery. However, few reports have focused on the degrees of degradation of the ingested proteins due to post-exercise glycogen resynthesis. Accordingly, the aim of this study was to clarify the effects of differences in protein degradation on muscle glycogen recovery. Male seven-week-old C57BL/6J mice performed a single bout of 60-min treadmill running exercise and were then orally administered glucose (Glu; 1.5 mg/g body weight (BW)), glucose with casein peptide (Glu + Pep; 1.5 + 0.5 mg/g BW) or its constituent amino acid mixture (Glu + AA; 1.5 + 0.5 mg/g BW). At 120 min after supplementation, the soleus muscle glycogen content in the Glu and Glu + AA groups was significantly higher than that immediately after exercise; however, no such difference was observed in the Glu + Pep group. Blood substrate concentration and insulin signaling did not differ among the three groups. Furthermore, energy expenditure during the recovery period in the Glu + Pep group was significantly higher than that in the Glu and Glu + AA groups. These findings suggest that post-exercise co-ingestion of glucose and casein peptide might delay glycogen resynthesis, at least in part through increased energy expenditure caused by casein peptide ingestion. MDPI 2018-06-11 /pmc/articles/PMC6024860/ /pubmed/29891805 http://dx.doi.org/10.3390/nu10060753 Text en © 2018 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Matsunaga, Yutaka
Sakata, Yasuyuki
Yago, Takumi
Nakamura, Hirohiko
Shimizu, Takashi
Takeda, Yasuhiro
Effects of Glucose with Casein Peptide Supplementation on Post-Exercise Muscle Glycogen Resynthesis in C57BL/6J Mice
title Effects of Glucose with Casein Peptide Supplementation on Post-Exercise Muscle Glycogen Resynthesis in C57BL/6J Mice
title_full Effects of Glucose with Casein Peptide Supplementation on Post-Exercise Muscle Glycogen Resynthesis in C57BL/6J Mice
title_fullStr Effects of Glucose with Casein Peptide Supplementation on Post-Exercise Muscle Glycogen Resynthesis in C57BL/6J Mice
title_full_unstemmed Effects of Glucose with Casein Peptide Supplementation on Post-Exercise Muscle Glycogen Resynthesis in C57BL/6J Mice
title_short Effects of Glucose with Casein Peptide Supplementation on Post-Exercise Muscle Glycogen Resynthesis in C57BL/6J Mice
title_sort effects of glucose with casein peptide supplementation on post-exercise muscle glycogen resynthesis in c57bl/6j mice
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6024860/
https://www.ncbi.nlm.nih.gov/pubmed/29891805
http://dx.doi.org/10.3390/nu10060753
work_keys_str_mv AT matsunagayutaka effectsofglucosewithcaseinpeptidesupplementationonpostexercisemuscleglycogenresynthesisinc57bl6jmice
AT sakatayasuyuki effectsofglucosewithcaseinpeptidesupplementationonpostexercisemuscleglycogenresynthesisinc57bl6jmice
AT yagotakumi effectsofglucosewithcaseinpeptidesupplementationonpostexercisemuscleglycogenresynthesisinc57bl6jmice
AT nakamurahirohiko effectsofglucosewithcaseinpeptidesupplementationonpostexercisemuscleglycogenresynthesisinc57bl6jmice
AT shimizutakashi effectsofglucosewithcaseinpeptidesupplementationonpostexercisemuscleglycogenresynthesisinc57bl6jmice
AT takedayasuhiro effectsofglucosewithcaseinpeptidesupplementationonpostexercisemuscleglycogenresynthesisinc57bl6jmice