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Dietary Supplementation with a Magnesium-Rich Marine Mineral Blend Enhances the Diversity of Gastrointestinal Microbiota

Accumulating evidence demonstrates that dietary supplementation with functional food ingredients play a role in systemic and brain health as well as in healthy ageing. Conversely, deficiencies in calcium and magnesium as a result of the increasing prevalence of a high fat/high sugar “Western diet” h...

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Autores principales: Crowley, Erin K., Long-Smith, Caitriona M., Murphy, Amy, Patterson, Elaine, Murphy, Kiera, O’Gorman, Denise M., Stanton, Catherine, Nolan, Yvonne M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6024889/
https://www.ncbi.nlm.nih.gov/pubmed/29925774
http://dx.doi.org/10.3390/md16060216
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author Crowley, Erin K.
Long-Smith, Caitriona M.
Murphy, Amy
Patterson, Elaine
Murphy, Kiera
O’Gorman, Denise M.
Stanton, Catherine
Nolan, Yvonne M.
author_facet Crowley, Erin K.
Long-Smith, Caitriona M.
Murphy, Amy
Patterson, Elaine
Murphy, Kiera
O’Gorman, Denise M.
Stanton, Catherine
Nolan, Yvonne M.
author_sort Crowley, Erin K.
collection PubMed
description Accumulating evidence demonstrates that dietary supplementation with functional food ingredients play a role in systemic and brain health as well as in healthy ageing. Conversely, deficiencies in calcium and magnesium as a result of the increasing prevalence of a high fat/high sugar “Western diet” have been associated with health problems such as obesity, inflammatory bowel diseases, and cardiovascular diseases, as well as metabolic, immune, and psychiatric disorders. It is now recognized that modulating the diversity of gut microbiota, the population of intestinal bacteria, through dietary intervention can significantly impact upon gut health as well as systemic and brain health. In the current study, we show that supplementation with a seaweed and seawater-derived functional food ingredient rich in bioactive calcium and magnesium (0.1% supplementation) as well as 70 other trace elements, significantly enhanced the gut microbial diversity in adult male rats. Given the significant impact of gut microbiota on health, these results position this marine multi-mineral blend (MMB) as a promising digestive-health promoting functional food ingredient.
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spelling pubmed-60248892018-07-09 Dietary Supplementation with a Magnesium-Rich Marine Mineral Blend Enhances the Diversity of Gastrointestinal Microbiota Crowley, Erin K. Long-Smith, Caitriona M. Murphy, Amy Patterson, Elaine Murphy, Kiera O’Gorman, Denise M. Stanton, Catherine Nolan, Yvonne M. Mar Drugs Article Accumulating evidence demonstrates that dietary supplementation with functional food ingredients play a role in systemic and brain health as well as in healthy ageing. Conversely, deficiencies in calcium and magnesium as a result of the increasing prevalence of a high fat/high sugar “Western diet” have been associated with health problems such as obesity, inflammatory bowel diseases, and cardiovascular diseases, as well as metabolic, immune, and psychiatric disorders. It is now recognized that modulating the diversity of gut microbiota, the population of intestinal bacteria, through dietary intervention can significantly impact upon gut health as well as systemic and brain health. In the current study, we show that supplementation with a seaweed and seawater-derived functional food ingredient rich in bioactive calcium and magnesium (0.1% supplementation) as well as 70 other trace elements, significantly enhanced the gut microbial diversity in adult male rats. Given the significant impact of gut microbiota on health, these results position this marine multi-mineral blend (MMB) as a promising digestive-health promoting functional food ingredient. MDPI 2018-06-20 /pmc/articles/PMC6024889/ /pubmed/29925774 http://dx.doi.org/10.3390/md16060216 Text en © 2018 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Crowley, Erin K.
Long-Smith, Caitriona M.
Murphy, Amy
Patterson, Elaine
Murphy, Kiera
O’Gorman, Denise M.
Stanton, Catherine
Nolan, Yvonne M.
Dietary Supplementation with a Magnesium-Rich Marine Mineral Blend Enhances the Diversity of Gastrointestinal Microbiota
title Dietary Supplementation with a Magnesium-Rich Marine Mineral Blend Enhances the Diversity of Gastrointestinal Microbiota
title_full Dietary Supplementation with a Magnesium-Rich Marine Mineral Blend Enhances the Diversity of Gastrointestinal Microbiota
title_fullStr Dietary Supplementation with a Magnesium-Rich Marine Mineral Blend Enhances the Diversity of Gastrointestinal Microbiota
title_full_unstemmed Dietary Supplementation with a Magnesium-Rich Marine Mineral Blend Enhances the Diversity of Gastrointestinal Microbiota
title_short Dietary Supplementation with a Magnesium-Rich Marine Mineral Blend Enhances the Diversity of Gastrointestinal Microbiota
title_sort dietary supplementation with a magnesium-rich marine mineral blend enhances the diversity of gastrointestinal microbiota
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6024889/
https://www.ncbi.nlm.nih.gov/pubmed/29925774
http://dx.doi.org/10.3390/md16060216
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