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Dysregulated HAI-2 Plays an Important Role in Renal Cell Carcinoma Bone Metastasis through Ligand-Dependent MET Phosphorylation

MET, a c-met proto-oncogene product and hepatocyte growth factor (HGF) receptor, is known to play an important role in cancer progression, including bone metastasis. In a previous study, we reported increased expression of MET and matriptase, a novel activator of HGF, in bone metastasis. In this stu...

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Detalles Bibliográficos
Autores principales: Yamasaki, Koji, Mukai, Shoichiro, Sugie, Satoru, Nagai, Takahiro, Nakahara, Kozue, Kamibeppu, Toyoharu, Sakamoto, Hiromasa, Shibasaki, Noboru, Terada, Naoki, Toda, Yoshinobu, Kataoka, Hiroaki, Kamoto, Toshiyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6025049/
https://www.ncbi.nlm.nih.gov/pubmed/29890660
http://dx.doi.org/10.3390/cancers10060190