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Paraquat Exposure of Pregnant Women and Neonates in Agricultural Areas in Thailand
This study aimed to assess paraquat concentrations in the urine of women at 28 weeks of pregnancy, delivery and 2 months postpartum and in the meconium of neonates. In all, 79 pregnant women were recruited from three hospitals located in agricultural areas in Thailand. The subjects were interviewed...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6025106/ https://www.ncbi.nlm.nih.gov/pubmed/29865285 http://dx.doi.org/10.3390/ijerph15061163 |
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author | Konthonbut, Pajaree Kongtip, Pornpimol Nankongnab, Noppanun Tipayamongkholgul, Mathuros Yoosook, Witaya Woskie, Susan |
author_facet | Konthonbut, Pajaree Kongtip, Pornpimol Nankongnab, Noppanun Tipayamongkholgul, Mathuros Yoosook, Witaya Woskie, Susan |
author_sort | Konthonbut, Pajaree |
collection | PubMed |
description | This study aimed to assess paraquat concentrations in the urine of women at 28 weeks of pregnancy, delivery and 2 months postpartum and in the meconium of neonates. In all, 79 pregnant women were recruited from three hospitals located in agricultural areas in Thailand. The subjects were interviewed about personal characteristics, agricultural activities and pesticide use patterns. Paraquat was analyzed in urine and meconium using high performance liquid chromatography equipped with a fluorescence detector. The geometric mean (GSD) of urinary paraquat concentrations at 28 weeks of pregnancy, delivery and 2 months postpartum were 2.04 (4.22), 2.06 (5.04) and 2.42 (5.33) ng/mL, respectively. The urinary paraquat concentrations at 28 weeks of pregnancy, delivery and 2 months postpartum between agriculturist and non-agriculturist were not significantly different (p = 0.632, p = 0.915, p = 0.57, respectively). The geometric mean (GSD) of paraquat concentration in the meconium was 33.31 (4.59) ng/g. The factors predicting paraquat exposures among pregnant women and neonates included working outside, living near farmland, having family members who work on a farm, drinking well water and using herbicides or paraquat. |
format | Online Article Text |
id | pubmed-6025106 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-60251062018-07-16 Paraquat Exposure of Pregnant Women and Neonates in Agricultural Areas in Thailand Konthonbut, Pajaree Kongtip, Pornpimol Nankongnab, Noppanun Tipayamongkholgul, Mathuros Yoosook, Witaya Woskie, Susan Int J Environ Res Public Health Article This study aimed to assess paraquat concentrations in the urine of women at 28 weeks of pregnancy, delivery and 2 months postpartum and in the meconium of neonates. In all, 79 pregnant women were recruited from three hospitals located in agricultural areas in Thailand. The subjects were interviewed about personal characteristics, agricultural activities and pesticide use patterns. Paraquat was analyzed in urine and meconium using high performance liquid chromatography equipped with a fluorescence detector. The geometric mean (GSD) of urinary paraquat concentrations at 28 weeks of pregnancy, delivery and 2 months postpartum were 2.04 (4.22), 2.06 (5.04) and 2.42 (5.33) ng/mL, respectively. The urinary paraquat concentrations at 28 weeks of pregnancy, delivery and 2 months postpartum between agriculturist and non-agriculturist were not significantly different (p = 0.632, p = 0.915, p = 0.57, respectively). The geometric mean (GSD) of paraquat concentration in the meconium was 33.31 (4.59) ng/g. The factors predicting paraquat exposures among pregnant women and neonates included working outside, living near farmland, having family members who work on a farm, drinking well water and using herbicides or paraquat. MDPI 2018-06-03 2018-06 /pmc/articles/PMC6025106/ /pubmed/29865285 http://dx.doi.org/10.3390/ijerph15061163 Text en © 2018 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Konthonbut, Pajaree Kongtip, Pornpimol Nankongnab, Noppanun Tipayamongkholgul, Mathuros Yoosook, Witaya Woskie, Susan Paraquat Exposure of Pregnant Women and Neonates in Agricultural Areas in Thailand |
title | Paraquat Exposure of Pregnant Women and Neonates in Agricultural Areas in Thailand |
title_full | Paraquat Exposure of Pregnant Women and Neonates in Agricultural Areas in Thailand |
title_fullStr | Paraquat Exposure of Pregnant Women and Neonates in Agricultural Areas in Thailand |
title_full_unstemmed | Paraquat Exposure of Pregnant Women and Neonates in Agricultural Areas in Thailand |
title_short | Paraquat Exposure of Pregnant Women and Neonates in Agricultural Areas in Thailand |
title_sort | paraquat exposure of pregnant women and neonates in agricultural areas in thailand |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6025106/ https://www.ncbi.nlm.nih.gov/pubmed/29865285 http://dx.doi.org/10.3390/ijerph15061163 |
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