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Smenamide A Analogues. Synthesis and Biological Activity on Multiple Myeloma Cells

Smenamides are an intriguing class of peptide/polyketide molecules of marine origin showing antiproliferative activity against lung cancer Calu-1 cells at nanomolar concentrations through a clear pro-apoptotic mechanism. To probe the role of the activity-determining structural features, the 16-epi-a...

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Detalles Bibliográficos
Autores principales: Caso, Alessia, Laurenzana, Ilaria, Lamorte, Daniela, Trino, Stefania, Esposito, Germana, Piccialli, Vincenzo, Costantino, Valeria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6025564/
https://www.ncbi.nlm.nih.gov/pubmed/29899231
http://dx.doi.org/10.3390/md16060206