Cargando…

A Novel Atypical PKC-Iota Inhibitor, Echinochrome A, Enhances Cardiomyocyte Differentiation from Mouse Embryonic Stem Cells

Echinochrome A (EchA) is a marine bioproduct extracted from sea urchins having antioxidant, antimicrobial, anti-inflammatory, and chelating effects, and is the active component of the clinical drug histochrome. We investigated the potential use of Ech A for inducing cardiomyocyte differentiation fro...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kim, Hyoung Kyu, Cho, Sung Woo, Heo, Hye Jin, Jeong, Seung Hun, Kim, Min, Ko, Kyung Soo, Rhee, Byoung Doo, Mishchenko, Natalia P., Vasileva, Elena A., Fedoreyev, Sergey A., Stonik, Valentin A., Han, Jin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2018
Materias:	Communication
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6025622/ https://www.ncbi.nlm.nih.gov/pubmed/29865255 http://dx.doi.org/10.3390/md16060192

Ejemplares similares

Echinochrome A Prevents Diabetic Nephropathy by Inhibiting the PKC-Iota Pathway and Enhancing Renal Mitochondrial Function in db/db Mice
por: Pham, Trong Kha, et al.
Publicado: (2023)

Echinochrome A Protects Mitochondrial Function in Cardiomyocytes against Cardiotoxic Drugs
por: Jeong, Seung Hun, et al.
Publicado: (2014)

Multifaceted Clinical Effects of Echinochrome
por: Kim, Hyoung Kyu, et al.
Publicado: (2021)

Echinochrome A Increases Mitochondrial Mass and Function by Modulating Mitochondrial Biogenesis Regulatory Genes
por: Jeong, Seung Hun, et al.
Publicado: (2014)

Acetylcholinesterase Inhibitory Activity of Pigment Echinochrome A from Sea Urchin Scaphechinus mirabilis
por: Lee, Sung Ryul, et al.
Publicado: (2014)

Echinochrome A Treatment Alleviates Atopic Dermatitis-like Skin Lesions in NC/Nga Mice via IL-4 and IL-13 Suppression
por: Yun, Hyeong Rok, et al.
Publicado: (2021)

Multiple Effects of Echinochrome A on Selected Ion Channels Implicated in Skin Physiology
por: Kim, Sung Eun, et al.
Publicado: (2023)

Echinochrome A Reverses Kidney Abnormality and Reduces Blood Pressure in a Rat Model of Preeclampsia
por: Cui, Huixing, et al.
Publicado: (2022)

Effect of Echinochrome A on Submandibular Gland Dysfunction in Ovariectomized Rats
por: Kim, Ji-Min, et al.
Publicado: (2022)

Echinochrome A Attenuates Cerebral Ischemic Injury through Regulation of Cell Survival after Middle Cerebral Artery Occlusion in Rat
por: Kim, Ran, et al.
Publicado: (2019)

The Protective Effect of Echinochrome A on Extracellular Matrix of Vocal Folds in Ovariectomized Rats
por: Kim, Ji Min, et al.
Publicado: (2020)

Echinochrome A Inhibits Melanogenesis in B16F10 Cells by Downregulating CREB Signaling
por: Choi, Mi Ran, et al.
Publicado: (2022)

Regulation of Inflammation-Mediated Endothelial to Mesenchymal Transition with Echinochrome a for Improving Myocardial Dysfunction
por: Song, Byeong-Wook, et al.
Publicado: (2022)

Echinochrome A Protects against Ultraviolet B-induced Photoaging by Lowering Collagen Degradation and Inflammatory Cell Infiltration in Hairless Mice
por: Seol, Jung Eun, et al.
Publicado: (2021)

Implication of Echinochrome A in the Plasticity and Damage of Intestinal Epithelium
por: Ahn, Ji-Su, et al.
Publicado: (2022)

Echinochrome A Reduces Colitis in Mice and Induces In Vitro Generation of Regulatory Immune Cells
por: Oh, Su-Jeong, et al.
Publicado: (2019)

Echinochrome Prevents Sulfide Catabolism-Associated Chronic Heart Failure after Myocardial Infarction in Mice
por: Tang, Xiaokang, et al.
Publicado: (2023)

Echinochrome A Improves Exercise Capacity during Short-Term Endurance Training in Rats
por: Seo, Dae Yun, et al.
Publicado: (2015)

Echinochrome A Treatment Alleviates Fibrosis and Inflammation in Bleomycin-Induced Scleroderma
por: Park, Gyu-Tae, et al.
Publicado: (2021)

Isolation and Structure Determination of Echinochrome A Oxidative Degradation Products
por: Mishchenko, Natalia P., et al.
Publicado: (2020)

Spinochrome D Attenuates Doxorubicin-Induced Cardiomyocyte Death via Improving Glutathione Metabolism and Attenuating Oxidative Stress
por: Yoon, Chang Shin, et al.
Publicado: (2018)

Echinochrome A Promotes Ex Vivo Expansion of Peripheral Blood-Derived CD34(+) Cells, Potentially through Downregulation of ROS Production and Activation of the Src-Lyn-p110δ Pathway
por: Park, Ga-Bin, et al.
Publicado: (2019)

Antiviral and Antioxidant Properties of Echinochrome A
por: Fedoreyev, Sergey A., et al.
Publicado: (2018)

Development of Novel Pharmaceutical Forms of the Marine Bioactive Pigment Echinochrome A Enabling Alternative Routes of Administration
por: Kikionis, Stefanos, et al.
Publicado: (2023)

Atypical PKC-iota Controls Stem Cell Expansion via Regulation of the Notch Pathway
por: Mah, In Kyoung, et al.
Publicado: (2015)

Liposomal Form of the Echinochrome-Carrageenan Complex
por: Yermak, Irina M., et al.
Publicado: (2018)

Effects of Carrageenans on Biological Properties of Echinochrome
por: Sokolova, Ekaterina V., et al.
Publicado: (2018)

Mitochondrial pyruvate dehydrogenase phosphatase 1 regulates the early differentiation of cardiomyocytes from mouse embryonic stem cells
por: Heo, Hye Jin, et al.
Publicado: (2016)

THE EXTRACELLULAR RELEASE OF ECHINOCHROME
por: Shapiro, Herbert
Publicado: (1946)

Atypical protein kinase C iota (PKCλ/ι) ensures mammalian development by establishing the maternal–fetal exchange interface
por: Bhattacharya, Bhaswati, et al.
Publicado: (2020)

PKC iota promotes ovarian tumor progression through deregulation of cyclin E
por: Nanos-Webb, Angela, et al.
Publicado: (2015)

Gli activation by aPKC iota/lambda regulates basal cell carcinoma growth
por: Atwood, Scott X., et al.
Publicado: (2013)

Histochrome Attenuates Myocardial Ischemia-Reperfusion Injury by Inhibiting Ferroptosis-Induced Cardiomyocyte Death
por: Hwang, Ji-Won, et al.
Publicado: (2021)

Atypical PKC and Notch Inhibition Differentially Modulate Cortical Interneuron Subclass Fate from Embryonic Stem Cells
por: Tischfield, David J., et al.
Publicado: (2017)

Effectiveness of Echinochrome on HFD-Induced Hyperlipidemia in Rats
por: Fahmy, Sohair R., et al.
Publicado: (2019)

PKG and PKC Are Down-Regulated during Cardiomyocyte Differentiation from Embryonic Stem Cells: Manipulation of These Pathways Enhances Cardiomyocyte Production
por: Mobley, Stephen, et al.
Publicado: (2010)

The Anti-Inflammatory Effect of Carrageenan/Echinochrom Complex at Experimental Endotoxemia
por: Yermak, Irina M., et al.
Publicado: (2022)

Tomatidine-stimulated maturation of human embryonic stem cell-derived cardiomyocytes for modeling mitochondrial dysfunction
por: Kim, Ye Seul, et al.
Publicado: (2022)

Spinochrome Identification and Quantification in Pacific Sea Urchin Shells, Coelomic Fluid and Eggs Using HPLC-DAD-MS
por: Vasileva, Elena A., et al.
Publicado: (2021)

Carrageenans-Sulfated Polysaccharides from Red Seaweeds as Matrices for the Inclusion of Echinochrome
por: Yermak, Irina M., et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_600nh83baimo3335ctm0ppqfp4