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Supervillin promotes epithelial-mesenchymal transition and metastasis of hepatocellular carcinoma in hypoxia via activation of the RhoA/ROCK-ERK/p38 pathway

BACKGROUND: Hepatocellular carcinoma (HCC) is one of the most common malignant tumors in the world and metastasis is the leading cause of death associated with HCC. Hypoxia triggers the epithelial-mesenchymal transition (EMT) of cancer cells, which enhances their malignant character and elevates met...

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Detalles Bibliográficos
Autores principales:	Chen, Xueran, Zhang, Shangrong, Wang, Zhen, Wang, Fengsong, Cao, Xinwang, Wu, Quan, Zhao, Chenggang, Ma, Huihui, Ye, Fang, Wang, Hongzhi, Fang, Zhiyou
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2018
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6025706/ https://www.ncbi.nlm.nih.gov/pubmed/29954442 http://dx.doi.org/10.1186/s13046-018-0787-2

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