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Quantitative proteomics of acutely-isolated mouse microglia identifies novel immune Alzheimer’s disease-related proteins

BACKGROUND: Microglia are innate immune cells of the brain that perform phagocytic and inflammatory functions in disease conditions. Transcriptomic studies of acutely-isolated microglia have provided novel insights into their molecular and functional diversity in homeostatic and neurodegenerative di...

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Detalles Bibliográficos
Autores principales: Rangaraju, Srikant, Dammer, Eric B., Raza, Syed Ali, Gao, Tianwen, Xiao, Hailian, Betarbet, Ranjita, Duong, Duc M., Webster, James A., Hales, Chadwick M., Lah, James J., Levey, Allan I., Seyfried, Nicholas T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6025801/
https://www.ncbi.nlm.nih.gov/pubmed/29954413
http://dx.doi.org/10.1186/s13024-018-0266-4