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Tuberculosis co-infection and its associated factors among People living with HIV/AIDS attending antiretroviral therapy clinic in southern Ethiopia: a facility based retrospective study

OBJECTIVE: The study aimed to determine the prevalence and identify determinants of TB among People living with HIV/AIDS (PLWHAs) through reviewing and analyzing patient case files from the anti-retro viral treatment (ART) clinic of Yirgalem General Hospital, southern Ethiopia. RESULTS: Of the total...

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Detalles Bibliográficos
Autores principales: Negussie, Abel, Debalke, Damene, Belachew, Teshome, Tadesse, Fetlework
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6025838/
https://www.ncbi.nlm.nih.gov/pubmed/29954451
http://dx.doi.org/10.1186/s13104-018-3530-3
Descripción
Sumario:OBJECTIVE: The study aimed to determine the prevalence and identify determinants of TB among People living with HIV/AIDS (PLWHAs) through reviewing and analyzing patient case files from the anti-retro viral treatment (ART) clinic of Yirgalem General Hospital, southern Ethiopia. RESULTS: Of the total PLWHAs involved in the study, 51 (36.9%) of them were found to have TB, and of which, 37 (72.5%) were smear negative cases. The multivariate analysis showed that PLWHA’s who are at WHO clinical stage 3 (AOR = 5.82; 95% CI 1.04–32.30), CD4 level of 200–500 cells/mm(3) (AOR = 4.85; 95% CI 1.95–12.05) and < 200 cells/mm(3) (AOR = 7.34; 95% CI 2.75–19.58) at ART initiation, and who didn’t take INH prophylaxis (AOR = 12.36; 95% CI 4.47–34.14) were significantly associated with TB-HIV co-infection. Rapid and sensitive diagnostic techniques should be implemented to early detect co-infections, and also INH prophylactic preventive measures should be strengthened to reduce TB incidence. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (10.1186/s13104-018-3530-3) contains supplementary material, which is available to authorized users.