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Tuberculosis co-infection and its associated factors among People living with HIV/AIDS attending antiretroviral therapy clinic in southern Ethiopia: a facility based retrospective study
OBJECTIVE: The study aimed to determine the prevalence and identify determinants of TB among People living with HIV/AIDS (PLWHAs) through reviewing and analyzing patient case files from the anti-retro viral treatment (ART) clinic of Yirgalem General Hospital, southern Ethiopia. RESULTS: Of the total...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6025838/ https://www.ncbi.nlm.nih.gov/pubmed/29954451 http://dx.doi.org/10.1186/s13104-018-3530-3 |
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author | Negussie, Abel Debalke, Damene Belachew, Teshome Tadesse, Fetlework |
author_facet | Negussie, Abel Debalke, Damene Belachew, Teshome Tadesse, Fetlework |
author_sort | Negussie, Abel |
collection | PubMed |
description | OBJECTIVE: The study aimed to determine the prevalence and identify determinants of TB among People living with HIV/AIDS (PLWHAs) through reviewing and analyzing patient case files from the anti-retro viral treatment (ART) clinic of Yirgalem General Hospital, southern Ethiopia. RESULTS: Of the total PLWHAs involved in the study, 51 (36.9%) of them were found to have TB, and of which, 37 (72.5%) were smear negative cases. The multivariate analysis showed that PLWHA’s who are at WHO clinical stage 3 (AOR = 5.82; 95% CI 1.04–32.30), CD4 level of 200–500 cells/mm(3) (AOR = 4.85; 95% CI 1.95–12.05) and < 200 cells/mm(3) (AOR = 7.34; 95% CI 2.75–19.58) at ART initiation, and who didn’t take INH prophylaxis (AOR = 12.36; 95% CI 4.47–34.14) were significantly associated with TB-HIV co-infection. Rapid and sensitive diagnostic techniques should be implemented to early detect co-infections, and also INH prophylactic preventive measures should be strengthened to reduce TB incidence. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (10.1186/s13104-018-3530-3) contains supplementary material, which is available to authorized users. |
format | Online Article Text |
id | pubmed-6025838 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-60258382018-07-09 Tuberculosis co-infection and its associated factors among People living with HIV/AIDS attending antiretroviral therapy clinic in southern Ethiopia: a facility based retrospective study Negussie, Abel Debalke, Damene Belachew, Teshome Tadesse, Fetlework BMC Res Notes Research Note OBJECTIVE: The study aimed to determine the prevalence and identify determinants of TB among People living with HIV/AIDS (PLWHAs) through reviewing and analyzing patient case files from the anti-retro viral treatment (ART) clinic of Yirgalem General Hospital, southern Ethiopia. RESULTS: Of the total PLWHAs involved in the study, 51 (36.9%) of them were found to have TB, and of which, 37 (72.5%) were smear negative cases. The multivariate analysis showed that PLWHA’s who are at WHO clinical stage 3 (AOR = 5.82; 95% CI 1.04–32.30), CD4 level of 200–500 cells/mm(3) (AOR = 4.85; 95% CI 1.95–12.05) and < 200 cells/mm(3) (AOR = 7.34; 95% CI 2.75–19.58) at ART initiation, and who didn’t take INH prophylaxis (AOR = 12.36; 95% CI 4.47–34.14) were significantly associated with TB-HIV co-infection. Rapid and sensitive diagnostic techniques should be implemented to early detect co-infections, and also INH prophylactic preventive measures should be strengthened to reduce TB incidence. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (10.1186/s13104-018-3530-3) contains supplementary material, which is available to authorized users. BioMed Central 2018-06-28 /pmc/articles/PMC6025838/ /pubmed/29954451 http://dx.doi.org/10.1186/s13104-018-3530-3 Text en © The Author(s) 2018 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated. |
spellingShingle | Research Note Negussie, Abel Debalke, Damene Belachew, Teshome Tadesse, Fetlework Tuberculosis co-infection and its associated factors among People living with HIV/AIDS attending antiretroviral therapy clinic in southern Ethiopia: a facility based retrospective study |
title | Tuberculosis co-infection and its associated factors among People living with HIV/AIDS attending antiretroviral therapy clinic in southern Ethiopia: a facility based retrospective study |
title_full | Tuberculosis co-infection and its associated factors among People living with HIV/AIDS attending antiretroviral therapy clinic in southern Ethiopia: a facility based retrospective study |
title_fullStr | Tuberculosis co-infection and its associated factors among People living with HIV/AIDS attending antiretroviral therapy clinic in southern Ethiopia: a facility based retrospective study |
title_full_unstemmed | Tuberculosis co-infection and its associated factors among People living with HIV/AIDS attending antiretroviral therapy clinic in southern Ethiopia: a facility based retrospective study |
title_short | Tuberculosis co-infection and its associated factors among People living with HIV/AIDS attending antiretroviral therapy clinic in southern Ethiopia: a facility based retrospective study |
title_sort | tuberculosis co-infection and its associated factors among people living with hiv/aids attending antiretroviral therapy clinic in southern ethiopia: a facility based retrospective study |
topic | Research Note |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6025838/ https://www.ncbi.nlm.nih.gov/pubmed/29954451 http://dx.doi.org/10.1186/s13104-018-3530-3 |
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