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Mechanical evolution of DNA double-strand breaks in the nucleosome

Double strand breaks (DSB) in the DNA backbone are the most lethal type of defect induced in the cell nucleus by chemical and radiation treatments of cancer. However, little is known about the outcomes of damage in nucleosomal DNA, and on its effects on damage repair. We performed microsecond-long m...

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Detalles Bibliográficos
Autores principales:	Cleri, Fabrizio, Landuzzi, Fabio, Blossey, Ralf
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6025874/ https://www.ncbi.nlm.nih.gov/pubmed/29902181 http://dx.doi.org/10.1371/journal.pcbi.1006224

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