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Genetic manipulation of Leishmania donovani threonyl tRNA synthetase facilitates its exploration as a potential therapeutic target

BACKGROUND: Aminoacyl tRNA synthetases are central enzymes required for protein synthesis. These enzymes are the known drug targets in bacteria and fungi. Here, we for the first time report the functional characterization of threonyl tRNA synthetase (LdThrRS) of Leishmania donovani, a protozoan para...

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Detalles Bibliográficos
Autores principales:	Chadha, Sanya, Vijayan, Ramachandran, Gupta, Sakshi, Munde, Manoj, Gourinath, Samudrala, Madhubala, Rentala
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6025875/ https://www.ncbi.nlm.nih.gov/pubmed/29897900 http://dx.doi.org/10.1371/journal.pntd.0006575

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