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Dietary rescue of lipotoxicity-induced mitochondrial damage in Peroxin19 mutants

Mutations in peroxin (PEX) genes lead to loss of peroxisomes, resulting in the formation of peroxisomal biogenesis disorders (PBDs) and early lethality. Studying PBDs and their animal models has greatly contributed to our current knowledge about peroxisomal functions. Very-long-chain fatty acid (VLC...

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Detalles Bibliográficos
Autores principales: Sellin, Julia, Wingen, Christian, Gosejacob, Dominic, Senyilmaz, Deniz, Hänschke, Lea, Büttner, Sven, Meyer, Katharina, Bano, Daniele, Nicotera, Pierluigi, Teleman, Aurelio A., Bülow, Margret H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6025876/
https://www.ncbi.nlm.nih.gov/pubmed/29920513
http://dx.doi.org/10.1371/journal.pbio.2004893

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