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The neuronal S100B protein is a calcium-tuned suppressor of amyloid-β aggregation

Amyloid-β (Aβ) aggregation and neuroinflammation are consistent features in Alzheimer’s disease (AD) and strong candidates for the initiation of neurodegeneration. S100B is one of the most abundant proinflammatory proteins that is chronically up-regulated in AD and is found associated with senile pl...

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Detalles Bibliográficos
Autores principales: Cristóvão, Joana S., Morris, Vanessa K., Cardoso, Isabel, Leal, Sónia S., Martínez, Javier, Botelho, Hugo M., Göbl, Christoph, David, Rodrigo, Kierdorf, Katrin, Alemi, Mobina, Madl, Tobias, Fritz, Günter, Reif, Bernd, Gomes, Cláudio M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6025902/
https://www.ncbi.nlm.nih.gov/pubmed/29963623
http://dx.doi.org/10.1126/sciadv.aaq1702