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The neuronal S100B protein is a calcium-tuned suppressor of amyloid-β aggregation
Amyloid-β (Aβ) aggregation and neuroinflammation are consistent features in Alzheimer’s disease (AD) and strong candidates for the initiation of neurodegeneration. S100B is one of the most abundant proinflammatory proteins that is chronically up-regulated in AD and is found associated with senile pl...
Autores principales: | Cristóvão, Joana S., Morris, Vanessa K., Cardoso, Isabel, Leal, Sónia S., Martínez, Javier, Botelho, Hugo M., Göbl, Christoph, David, Rodrigo, Kierdorf, Katrin, Alemi, Mobina, Madl, Tobias, Fritz, Günter, Reif, Bernd, Gomes, Cláudio M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Association for the Advancement of Science
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6025902/ https://www.ncbi.nlm.nih.gov/pubmed/29963623 http://dx.doi.org/10.1126/sciadv.aaq1702 |
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