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Inward growth by nucleation: Multiscale self-assembly of ordered membranes

Striking morphological similarities found between superstructures of a wide variety of seemingly unrelated crystalline membrane systems hint at the existence of a common formation mechanism. Resembling systems such as multiwalled carbon nanotubes, bacterial protein shells, or peptide nanotubes, the...

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Autores principales: Landman, Jasper, Ouhajji, Samia, Prévost, Sylvain, Narayanan, Theyencheri, Groenewold, Jan, Philipse, Albert P., Kegel, Willem K., Petukhov, Andrei V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6025906/
https://www.ncbi.nlm.nih.gov/pubmed/29963633
http://dx.doi.org/10.1126/sciadv.aat1817
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author Landman, Jasper
Ouhajji, Samia
Prévost, Sylvain
Narayanan, Theyencheri
Groenewold, Jan
Philipse, Albert P.
Kegel, Willem K.
Petukhov, Andrei V.
author_facet Landman, Jasper
Ouhajji, Samia
Prévost, Sylvain
Narayanan, Theyencheri
Groenewold, Jan
Philipse, Albert P.
Kegel, Willem K.
Petukhov, Andrei V.
author_sort Landman, Jasper
collection PubMed
description Striking morphological similarities found between superstructures of a wide variety of seemingly unrelated crystalline membrane systems hint at the existence of a common formation mechanism. Resembling systems such as multiwalled carbon nanotubes, bacterial protein shells, or peptide nanotubes, the self-assembly of SDS/β-cyclodextrin complexes leads to monodisperse multilamellar microtubes. We uncover the mechanism of this hierarchical self-assembly process by time-resolved small- and ultrasmall-angle x-ray scattering. In particular, we show that symmetric crystalline bilayers bend into hollow cylinders as a consequence of membrane line tension and an anisotropic elastic modulus. Starting from single-walled microtubes, successive nucleation of new cylinders inside preexisting ones drives an inward growth. As both the driving forces that underlie the self-assembly behavior and the resulting morphologies are common to systems of ordered membranes, we believe that this formation mechanism has a similarly general applicability.
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spelling pubmed-60259062018-06-30 Inward growth by nucleation: Multiscale self-assembly of ordered membranes Landman, Jasper Ouhajji, Samia Prévost, Sylvain Narayanan, Theyencheri Groenewold, Jan Philipse, Albert P. Kegel, Willem K. Petukhov, Andrei V. Sci Adv Research Articles Striking morphological similarities found between superstructures of a wide variety of seemingly unrelated crystalline membrane systems hint at the existence of a common formation mechanism. Resembling systems such as multiwalled carbon nanotubes, bacterial protein shells, or peptide nanotubes, the self-assembly of SDS/β-cyclodextrin complexes leads to monodisperse multilamellar microtubes. We uncover the mechanism of this hierarchical self-assembly process by time-resolved small- and ultrasmall-angle x-ray scattering. In particular, we show that symmetric crystalline bilayers bend into hollow cylinders as a consequence of membrane line tension and an anisotropic elastic modulus. Starting from single-walled microtubes, successive nucleation of new cylinders inside preexisting ones drives an inward growth. As both the driving forces that underlie the self-assembly behavior and the resulting morphologies are common to systems of ordered membranes, we believe that this formation mechanism has a similarly general applicability. American Association for the Advancement of Science 2018-06-29 /pmc/articles/PMC6025906/ /pubmed/29963633 http://dx.doi.org/10.1126/sciadv.aat1817 Text en Copyright © 2018 The Authors, some rights reserved; exclusive licensee American Association for the Advancement of Science. No claim to original U.S. Government Works. Distributed under a Creative Commons Attribution NonCommercial License 4.0 (CC BY-NC). http://creativecommons.org/licenses/by-nc/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial license (http://creativecommons.org/licenses/by-nc/4.0/) , which permits use, distribution, and reproduction in any medium, so long as the resultant use is not for commercial advantage and provided the original work is properly cited.
spellingShingle Research Articles
Landman, Jasper
Ouhajji, Samia
Prévost, Sylvain
Narayanan, Theyencheri
Groenewold, Jan
Philipse, Albert P.
Kegel, Willem K.
Petukhov, Andrei V.
Inward growth by nucleation: Multiscale self-assembly of ordered membranes
title Inward growth by nucleation: Multiscale self-assembly of ordered membranes
title_full Inward growth by nucleation: Multiscale self-assembly of ordered membranes
title_fullStr Inward growth by nucleation: Multiscale self-assembly of ordered membranes
title_full_unstemmed Inward growth by nucleation: Multiscale self-assembly of ordered membranes
title_short Inward growth by nucleation: Multiscale self-assembly of ordered membranes
title_sort inward growth by nucleation: multiscale self-assembly of ordered membranes
topic Research Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6025906/
https://www.ncbi.nlm.nih.gov/pubmed/29963633
http://dx.doi.org/10.1126/sciadv.aat1817
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