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Permselectivity limits of biomimetic desalination membranes
Water scarcity and inadequate membrane selectivity have spurred interest in biomimetic desalination membranes, in which biological or synthetic water channels are incorporated in an amphiphilic bilayer. As low channel densities (0.1 to 10%) are required for sufficient water permeability, the amphiph...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Association for the Advancement of Science
2018
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6025908/ https://www.ncbi.nlm.nih.gov/pubmed/29963628 http://dx.doi.org/10.1126/sciadv.aar8266 |
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author | Werber, Jay R. Elimelech, Menachem |
author_facet | Werber, Jay R. Elimelech, Menachem |
author_sort | Werber, Jay R. |
collection | PubMed |
description | Water scarcity and inadequate membrane selectivity have spurred interest in biomimetic desalination membranes, in which biological or synthetic water channels are incorporated in an amphiphilic bilayer. As low channel densities (0.1 to 10%) are required for sufficient water permeability, the amphiphilic bilayer matrix will play a critical role in separation performance. We determine selectivity limits for biomimetic membranes by studying the transport behavior of water, neutral solutes, and ions through the bilayers of lipid and block-copolymer vesicles and projecting performance for varying water channel densities. We report that defect-free biomimetic membranes would have water/salt permselectivities ~10(8)-fold greater than current desalination membranes. In contrast, the solubility-based permeability of lipid and block-copolymer bilayers (extending Overton’s rule) will result in poor rejection of hydrophobic solutes. Defect-free biomimetic membranes thus offer great potential for seawater desalination and ultrapure water production, but would perform poorly in wastewater reuse. Potential strategies to limit neutral solute permeation are discussed. |
format | Online Article Text |
id | pubmed-6025908 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | American Association for the Advancement of Science |
record_format | MEDLINE/PubMed |
spelling | pubmed-60259082018-06-30 Permselectivity limits of biomimetic desalination membranes Werber, Jay R. Elimelech, Menachem Sci Adv Research Articles Water scarcity and inadequate membrane selectivity have spurred interest in biomimetic desalination membranes, in which biological or synthetic water channels are incorporated in an amphiphilic bilayer. As low channel densities (0.1 to 10%) are required for sufficient water permeability, the amphiphilic bilayer matrix will play a critical role in separation performance. We determine selectivity limits for biomimetic membranes by studying the transport behavior of water, neutral solutes, and ions through the bilayers of lipid and block-copolymer vesicles and projecting performance for varying water channel densities. We report that defect-free biomimetic membranes would have water/salt permselectivities ~10(8)-fold greater than current desalination membranes. In contrast, the solubility-based permeability of lipid and block-copolymer bilayers (extending Overton’s rule) will result in poor rejection of hydrophobic solutes. Defect-free biomimetic membranes thus offer great potential for seawater desalination and ultrapure water production, but would perform poorly in wastewater reuse. Potential strategies to limit neutral solute permeation are discussed. American Association for the Advancement of Science 2018-06-29 /pmc/articles/PMC6025908/ /pubmed/29963628 http://dx.doi.org/10.1126/sciadv.aar8266 Text en Copyright © 2018 The Authors, some rights reserved; exclusive licensee American Association for the Advancement of Science. No claim to original U.S. Government Works. Distributed under a Creative Commons Attribution NonCommercial License 4.0 (CC BY-NC). http://creativecommons.org/licenses/by-nc/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial license (http://creativecommons.org/licenses/by-nc/4.0/) , which permits use, distribution, and reproduction in any medium, so long as the resultant use is not for commercial advantage and provided the original work is properly cited. |
spellingShingle | Research Articles Werber, Jay R. Elimelech, Menachem Permselectivity limits of biomimetic desalination membranes |
title | Permselectivity limits of biomimetic desalination membranes |
title_full | Permselectivity limits of biomimetic desalination membranes |
title_fullStr | Permselectivity limits of biomimetic desalination membranes |
title_full_unstemmed | Permselectivity limits of biomimetic desalination membranes |
title_short | Permselectivity limits of biomimetic desalination membranes |
title_sort | permselectivity limits of biomimetic desalination membranes |
topic | Research Articles |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6025908/ https://www.ncbi.nlm.nih.gov/pubmed/29963628 http://dx.doi.org/10.1126/sciadv.aar8266 |
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