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Age-Related Declines in Prefrontal Cortical Expression of Metabotropic Glutamate Receptors that Support Working Memory
Glutamate signaling is essential for the persistent neural activity in prefrontal cortex (PFC) that enables working memory. Metabotropic glutamate receptors (mGluRs) are a diverse class of proteins that modulate excitatory neurotransmission via both presynaptic regulation of extracellular glutamate...
Autores principales: | Hernandez, Caesar M., McQuail, Joseph A., Schwabe, Miranda R., Burke, Sara N., Setlow, Barry, Bizon, Jennifer L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Society for Neuroscience
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6026020/ https://www.ncbi.nlm.nih.gov/pubmed/29971246 http://dx.doi.org/10.1523/ENEURO.0164-18.2018 |
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