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Using Automated Live Cell Imaging to Reveal Early Changes during Human Motor Neuron Degeneration
Human neurons expressing mutations associated with neurodegenerative disease are becoming more widely available. Hence, developing assays capable of accurately detecting changes that occur early in the disease process and identifying therapeutics able to slow these changes should become ever more im...
Autores principales: | Shin, Hye Young, Pfaff, Kathleen L., Davidow, Lance S., Sun, Chicheng, Uozumi, Takayuki, Yanagawa, Fumiki, Yamazaki, Yoichi, Kiyota, Yasujiro, Rubin, Lee L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Society for Neuroscience
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6026021/ https://www.ncbi.nlm.nih.gov/pubmed/29971247 http://dx.doi.org/10.1523/ENEURO.0001-18.2018 |
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