Cargando…

A naturally occurring antiviral ribonucleotide encoded by the human genome

Viral infections continue to represent major public health challenges, demanding enhanced mechanistic understanding of the processes contributing to viral lifecycles for the realization of new therapeutic strategies(1). Viperin, a member of the radical S-adenosyl-L-methionine (SAM) superfamily of en...

Descripción completa

Detalles Bibliográficos
Autores principales:	Gizzi, Anthony S., Grove, Tyler L., Arnold, Jamie J., Jose, Joyce, Jangra, Rohit K, Garforth, Scott J., Du, Quan, Cahill, Sean M., Dulyaninova, Natalya G., Love, James D., Chandran, Kartik, Bresnick, Anne R., Cameron, Craig E., Almo, Steven C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6026066/ https://www.ncbi.nlm.nih.gov/pubmed/29925952 http://dx.doi.org/10.1038/s41586-018-0238-4

Ejemplares similares

S100A4 Regulates Macrophage Chemotaxis
por: Li, Zhong-Hua, et al.
Publicado: (2010)

Structure of the S100A4/myosin-IIA complex
por: Ramagopal, Udupi A, et al.
Publicado: (2013)

S100A4 regulates macrophage invasion by distinct myosin-dependent and myosin-independent mechanisms
por: Dulyaninova, Natalya G., et al.
Publicado: (2018)

Direct Visualization of Ebola Virus Fusion Triggering in the Endocytic Pathway
por: Spence, Jennifer S., et al.
Publicado: (2016)

Two Point Mutations in Old World Hantavirus Glycoproteins Afford the Generation of Highly Infectious Recombinant Vesicular Stomatitis Virus Vectors
por: Slough, Megan M., et al.
Publicado: (2019)

Additive CHARMM force field for naturally occurring modified ribonucleotides
por: Xu, You, et al.
Publicado: (2016)

Cell-impermeable staurosporine analog targets extracellular kinases to inhibit HSV and SARS-CoV-2
por: Cheshenko, Natalia, et al.
Publicado: (2022)

Author Correction: Cell-impermeable staurosporine analog targets extracellular kinases to inhibit HSV and SARS-CoV-2
por: Cheshenko, Natalia, et al.
Publicado: (2023)

Direct Intracellular Visualization of Ebola Virus-Receptor Interaction by In Situ Proximity Ligation
por: Mittler, Eva, et al.
Publicado: (2021)

Vaccinia Virus–Encoded Ribonucleotide Reductase Subunits Are Differentially Required for Replication and Pathogenesis
por: Gammon, Don B., et al.
Publicado: (2010)

Immune responses to SARS-CoV-2 infection in hospitalized pediatric and adult patients
por: Pierce, Carl A., et al.
Publicado: (2020)

A Glycoprotein Mutation That Emerged during the 2013–2016 Ebola Virus Epidemic Alters Proteolysis and Accelerates Membrane Fusion
por: Fels, J. Maximilian, et al.
Publicado: (2021)

Ribonucleases and Ribonucleotides in Liver Tumours
por: Reid, E., et al.
Publicado: (1958)

The Origin and Evolution of Ribonucleotide Reduction
por: Lundin, Daniel, et al.
Publicado: (2015)

Convergent allostery in ribonucleotide reductase
por: Thomas, William C., et al.
Publicado: (2019)

The periodic table of ribonucleotide reductases
por: Ruskoski, Terry B., et al.
Publicado: (2021)

Naturally Occurring Bioactives as Antivirals: Emphasis on Coronavirus Infection
por: Ayatollahi, Seyed Abdulmajid, et al.
Publicado: (2021)

Ribonucleotide reductase, a novel drug target for gonorrhea
por: Narasimhan, Jana, et al.
Publicado: (2022)

Identification of a novel tRNA wobble uridine modifying activity in the biosynthesis of 5-methoxyuridine
por: Ryu, Huijeong, et al.
Publicado: (2018)

Azo-Dye Carcinogenesis: Ribonucleotides and Ribonucleases
por: Nodes, J. T., et al.
Publicado: (1963)

The tyrosyl free radical in ribonucleotide reductase.
por: Gräslund, A, et al.
Publicado: (1985)

Mutagenic cost of ribonucleotides in bacterial DNA
por: Schroeder, Jeremy W., et al.
Publicado: (2017)

Stereoselective Synthesis of β-Glycinamide Ribonucleotide
por: Ngu, Lisa, et al.
Publicado: (2022)

The identification of viral ribonucleotide reductase encoded by ORF23 and ORF141 genes and effect on CyHV-2 replication
por: Cheng, Wenjie, et al.
Publicado: (2023)

Iron Chelator Transmetalative Approach to Inhibit Human Ribonucleotide Reductase
por: Gaur, Kavita, et al.
Publicado: (2021)

Emerging Roles of Viroporins Encoded by DNA Viruses: Novel Targets for Antivirals?
por: Royle, Jamie, et al.
Publicado: (2015)

High density of unrepaired genomic ribonucleotides leads to Topoisomerase 1-mediated severe growth defects in absence of ribonucleotide reductase
por: Cerritelli, Susana M, et al.
Publicado: (2020)

Oral Vaccination With Recombinant Vesicular Stomatitis Virus Expressing Sin Nombre Virus Glycoprotein Prevents Sin Nombre Virus Transmission in Deer Mice
por: Warner, Bryce M., et al.
Publicado: (2020)

ADP-Ribosylation and Antiviral Resistance in Plants
por: Spechenkova, Nadezhda, et al.
Publicado: (2023)

Ribonucleotide and R-Loop Damage in Plastid DNA and Mitochondrial DNA during Maize Development
por: Tripathi, Diwaker, et al.
Publicado: (2023)

The small subunit of ribonucleotide reductase is encoded by one of the most abundant translationally regulated maternal RNAs in clam and sea urchin eggs
Publicado: (1985)

Maize LOST SUBSIDIARY CELL encoding a large subunit of ribonucleotide reductase is required for subsidiary cell development and plant growth
por: Cui, Yongqi, et al.
Publicado: (2023)

Rational polynomial representation of ribonucleotide reductase activity
por: Radivoyevitch, Tomas, et al.
Publicado: (2005)

Genome instability due to ribonucleotide incorporation into DNA
por: Nick McElhinny, Stephanie A., et al.
Publicado: (2010)

HAMR: high-throughput annotation of modified ribonucleotides
por: Ryvkin, Paul, et al.
Publicado: (2013)

Out of S-phase: Shift of subunits for ribonucleotide reduction
por: Pontarin, Giovanna, et al.
Publicado: (2012)

Ribonucleotide reductases: essential enzymes for bacterial life
por: Torrents, Eduard
Publicado: (2014)

Modulating pyrimidine ribonucleotide levels for the treatment of cancer
por: Mollick, Tanzina, et al.
Publicado: (2020)

Validation strategies for antibodies targeting modified ribonucleotides
por: Weichmann, Franziska, et al.
Publicado: (2020)

Evaluation of repair activity by quantification of ribonucleotides in the genome
por: Iida, Tetsushi, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_ns2u5u1bc81hg9v9f7psigokok