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S100B immunization triggers NFκB and complement activation in an autoimmune glaucoma model
In glaucoma, latest studies revealed an involvement of the complement system with and without an elevated intraocular pressure. In the experimental autoimmune glaucoma model, immunization with antigens, such as S100B, lead to retinal ganglion cell (RGC) loss and optic nerve degeneration after 28 day...
Autores principales: | Reinehr, Sabrina, Reinhard, Jacqueline, Gandej, Marcel, Gottschalk, Ivo, Stute, Gesa, Faissner, Andreas, Dick, H. Burkhard, Joachim, Stephanie C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6026137/ https://www.ncbi.nlm.nih.gov/pubmed/29959432 http://dx.doi.org/10.1038/s41598-018-28183-6 |
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