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Age-related differences in humoral and cellular immune responses after primary immunisation: indications for stratified vaccination schedules
Immunosenescence is characterised by reduced B and T cell responses. Evidence shows that booster vaccinations are less effective in elderly people, but data on the efficacy of primary immunisation are sparse. We conducted a monocentric, open label, phase IV trial to compare immune responses to prima...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6026142/ https://www.ncbi.nlm.nih.gov/pubmed/29959387 http://dx.doi.org/10.1038/s41598-018-28111-8 |