Morphological, genomic and transcriptomic responses of Klebsiella pneumoniae to the last-line antibiotic colistin

Colistin remains one of the few antibiotics effective against multi-drug resistant (MDR) hospital pathogens, such as Klebsiella pneumoniae. Yet resistance to this last-line drug is rapidly increasing. Characterized mechanisms of col(R) in K. pneumoniae are largely due to chromosomal mutations in two...

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Detalles Bibliográficos
Autores principales: Cain, Amy K., Boinett, Christine J., Barquist, Lars, Dordel, Janina, Fookes, Maria, Mayho, Matthew, Ellington, Matthew J., Goulding, David, Pickard, Derek, Wick, Ryan R., Holt, Kathryn E., Parkhill, Julian, Thomson, Nicholas R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6026146/
https://www.ncbi.nlm.nih.gov/pubmed/29959380
http://dx.doi.org/10.1038/s41598-018-28199-y

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