Cargando…

Conformation-dependent binding of a Tetrastatin peptide to α(v)β(3) integrin decreases melanoma progression through FAK/PI(3)K/Akt pathway inhibition

Tetrastatin, a 230 amino acid sequence from collagen IV, was previously demonstrated to inhibit melanoma progression. In the present paper, we identified the minimal active sequence (QKISRCQVCVKYS: QS-13) that reproduced the anti-tumor effects of whole Tetrastatin in vivo and in vitro on melanoma ce...

Descripción completa

Detalles Bibliográficos
Autores principales:	Lambert, Eléonore, Fuselier, Eloïse, Ramont, Laurent, Brassart, Bertrand, Dukic, Sylvain, Oudart, Jean-Baptiste, Dupont-Deshorgue, Aurélie, Sellier, Christèle, Machado, Carine, Dauchez, Manuel, Monboisse, Jean-Claude, Maquart, François-Xavier, Baud, Stéphanie, Brassart-Pasco, Sylvie
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6026150/ https://www.ncbi.nlm.nih.gov/pubmed/29959360 http://dx.doi.org/10.1038/s41598-018-28003-x

Ejemplares similares

The anti-tumor NC1 domain of collagen XIX inhibits the FAK/ PI3K/Akt/mTOR signaling pathway through αvβ3 integrin interaction
por: Oudart, Jean-Baptiste, et al.
Publicado: (2015)

Angiogenesis Inhibition by a Short 13 Amino Acid Peptide Sequence of Tetrastatin, the α4(IV) NC1 Domain of Collagen IV
por: Vautrin-Glabik, Alexia, et al.
Publicado: (2020)

Plasmin releases the anti-tumor peptide from the NC1 domain of collagen XIX
por: Oudart, Jean-Baptiste, et al.
Publicado: (2015)

F4, a collagen XIX-derived peptide, inhibits tumor angiogenesis through αvβ3 and α5β1 integrin interaction
por: Oudart, Jean-Baptiste, et al.
Publicado: (2021)

Tetrastatin, the NC1 Domain of the α4(IV) Collagen Chain: A Novel Potent Anti-Tumor Matrikine
por: Brassart-Pasco, Sylvie, et al.
Publicado: (2012)

Extracellular Vesicle-Dependent Cross-Talk in Cancer—Focus on Pancreatic Cancer
por: Nannan, Lise, et al.
Publicado: (2020)

Tumor Microenvironment: Extracellular Matrix Alterations Influence Tumor Progression
por: Brassart-Pasco, Sylvie, et al.
Publicado: (2020)

AG-9, an Elastin-Derived Peptide, Increases In Vitro Oral Tongue Carcinoma Cell Invasion, through an Increase in MMP-2 Secretion and MT1-MMP Expression, in a RPSA-Dependent Manner
por: Bretaudeau, Clara, et al.
Publicado: (2020)

Tumour cell blebbing and extracellular vesicle shedding: key role of matrikines and ribosomal protein SA
por: Brassart, Bertrand, et al.
Publicado: (2019)

Elastin peptides regulate HT-1080 fibrosarcoma cell migration and invasion through an Hsp90-dependent mechanism
por: Donet, M, et al.
Publicado: (2014)

Structural characterization and in vivo pro-tumor properties of a highly conserved matrikine
por: Da Silva, Jordan, et al.
Publicado: (2018)

L-Rhamnose and Phenolic Esters-Based Monocatenar and Bolaform Amphiphiles: Eco-Compatible Synthesis and Determination of Their Antioxidant, Eliciting and Cytotoxic Properties
por: Kordkatooli, Emad, et al.
Publicado: (2023)

Encapsulation of Vitamin C by Glycerol-Derived Dendrimers, Their Interaction with Biomimetic Models of Stratum corneum and Their Cytotoxicity
por: Bacha, Katia, et al.
Publicado: (2022)

Tau protein as a possible marker of cerebrospinal fluid leakage in cerebrospinal fluid rhinorrhoea: A pilot study
por: Oudart, Jean-Baptiste, et al.
Publicado: (2017)

TRPM7/RPSA Complex Regulates Pancreatic Cancer Cell Migration
por: Lefebvre, Thibaut, et al.
Publicado: (2020)

Synthesis and Activity of Ionic Antioxidant-Functionalized PAMAMs and PPIs Dendrimers
por: Bacha, Katia, et al.
Publicado: (2022)

A Rare Vascular Cause of Hoarseness
por: Calvaer, Florence, et al.
Publicado: (2020)

Ticagrelor Prevents Endothelial Cell Apoptosis through the Adenosine Signalling Pathway in the Early Stages of Hypoxia
por: Feliu, Catherine, et al.
Publicado: (2020)

Role of the interstitium during septic shock: a key to the understanding of fluid dynamics?
por: Dargent, Auguste, et al.
Publicado: (2023)

A rare vascular complication of Eagle syndrome highlight by CTA with neck flexion
por: BRASSART, Nicolas, et al.
Publicado: (2020)

Differential MMP-14 Targeting by Lumican-Derived Peptides Unraveled by In Silico Approach
por: Dauvé, Jonathan, et al.
Publicado: (2021)

Type I collagen aging impairs discoidin domain receptor 2-mediated tumor cell growth suppression
por: Saby, Charles, et al.
Publicado: (2016)

Do Failure of Posterior Tibial Nerve Stimulation Precludes to Use Sacral Neuromodulation in Patient With Overactive Bladder?
por: Berthelot, Louis-Paul, et al.
Publicado: (2019)

Focus on the Narrative Skills of Teenagers With Developmental Language Disorder and High Functioning Autism
por: Broc, Lucie, et al.
Publicado: (2021)

Commissioning and Implementation of the MEDICYC Cyclotron Programme
por: Mandrillon, P, et al.
Publicado: (1991)

Vertebral Artery Perforation as a Periprocedural Complication of Coronary Angiography
por: Zaher, Wael, et al.
Publicado: (2022)

Analyzing Intra-Cycle Velocity Profile and Trunk Inclination during Wheelchair Racing Propulsion
por: Poulet, Yoann, et al.
Publicado: (2022)

Bioresorbable Magnesium-Based Stent: Real-World Clinical Experience and Feasibility of Follow-Up by Coronary Computed Tomography: A New Window to Look at New Scaffolds
por: Ghafari, Chadi, et al.
Publicado: (2023)

Elastin-derived peptides enhance melanoma growth in vivo by upregulating the activation of Mcol-A (MMP-1) collagenase
por: Devy, J, et al.
Publicado: (2010)

Low-diluted Phenacetinum disrupted the melanoma cancer cell migration
por: Fuselier, Camille, et al.
Publicado: (2019)

Integrin-FAK signaling rapidly and potently promotes mitochondrial function through STAT3
por: Visavadiya, Nishant P., et al.
Publicado: (2016)

Multiscale modelling of the extracellular matrix
por: Wong, Hua, et al.
Publicado: (2021)

Occult renal artery pseudoaneurysm causing persistent hematuria after flexible Thulium fibered laser lithotripsy: A case report and literature review of rare but potentially fatal complication
por: Al Barajraji, Moncef, et al.
Publicado: (2023)

Assessment of Ovarian Tumor Growth in Wild-Type and Lumican-Deficient Mice: Insights Using Infrared Spectral Imaging, Histopathology, and Immunohistochemistry
por: Nizet, Pierre, et al.
Publicado: (2021)

A case of splenic rupture a week after appendectomy
por: Deleuze, Catherine, et al.
Publicado: (2021)

Influence of Wheelchair Type on Kinematic Parameters in Wheelchair Rugby
por: Bakatchina, Sadate, et al.
Publicado: (2022)

The FAK scaffold inhibitor C4 disrupts FAK-VEGFR-3 signaling and inhibits pancreatic cancer growth
por: Kurenova, Elena, et al.
Publicado: (2013)

Erratum to: Integrin-FAK signaling rapidly and potently promotes mitochondrial function through STAT3
por: Visavadiya, Nishant P., et al.
Publicado: (2017)

Correction to: Integrin-FAK signaling rapidly and potently promotes mitochondrial function through STAT3
por: Visavadiya, Nishant P., et al.
Publicado: (2020)

Technical specification - Vacuum tank for 3 FAK modules
Publicado: (1974)

Cannot write session to /tmp/vufind_sessions/sess_4oumlmuqu78gefuk5a2d6ou5qv