Targeting EZH2 reactivates a breast cancer subtype-specific anti-metastatic transcriptional program

Emerging evidence has illustrated the importance of epigenomic reprogramming in cancer, with altered post-translational modifications of histones contributing to pathogenesis. However, the contributions of histone modifiers to breast cancer progression are unclear, and how these processes vary betwe...

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Detalles Bibliográficos
Autores principales: Hirukawa, Alison, Smith, Harvey W., Zuo, Dongmei, Dufour, Catherine R., Savage, Paul, Bertos, Nicholas, Johnson, Radia M., Bui, Tung, Bourque, Guillaume, Basik, Mark, Giguère, Vincent, Park, Morag, Muller, William J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6026192/
https://www.ncbi.nlm.nih.gov/pubmed/29959321
http://dx.doi.org/10.1038/s41467-018-04864-8

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