Cargando…

Baseline characteristics, management practices, and long-term outcomes among patients with first presentation acute myocardial infarction in the Second Gulf Registry of Acute Coronary Events (Gulf RACE-II)

BACKGROUND AND OBJECTIVES: Limited data are available highlighting the different clinical aspects of acute coronary syndrome (ACS) patients, especially in Gulf countries. In this study, we aimed to compare patients who presented with acute myocardial infarction (AMI) as the first presentation of pat...

Descripción completa

Detalles Bibliográficos
Autores principales: Joury, Abdulaziz U., Hersi, Ahmed S., Alfaleh, Hussam, Alhabib, Khalid F., Kashour, Tarek Seifaw
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6026399/
https://www.ncbi.nlm.nih.gov/pubmed/29983497
http://dx.doi.org/10.1016/j.jsha.2018.03.001
_version_ 1783336433944100864
author Joury, Abdulaziz U.
Hersi, Ahmed S.
Alfaleh, Hussam
Alhabib, Khalid F.
Kashour, Tarek Seifaw
author_facet Joury, Abdulaziz U.
Hersi, Ahmed S.
Alfaleh, Hussam
Alhabib, Khalid F.
Kashour, Tarek Seifaw
author_sort Joury, Abdulaziz U.
collection PubMed
description BACKGROUND AND OBJECTIVES: Limited data are available highlighting the different clinical aspects of acute coronary syndrome (ACS) patients, especially in Gulf countries. In this study, we aimed to compare patients who presented with acute myocardial infarction (AMI) as the first presentation of patients who have a history of ACS in terms of initial presentation, medical history, laboratory findings, and overall mortality. METHODS: We used the Second Gulf Registry of Acute Coronary Events (Gulf RACE-II), which is a multinational observational study of 7930 ACS patients. RESULTS: Among all patients, 4723 (59.6%) patients presented with AMI. First presentation AMI patients were older (mean age, 55 years vs. 53 years; p < 0.001) and had lower risk factors than patients with a history of ACS. Higher laboratory readings of cardiac markers and all aspects of mortality were significantly higher among patients with first presentation AMI. After adjustments for baseline variables, congestive heart failure [odds ratio (OR) = 1.08; 95% confidence interval (CI), 0.73–1.57], reinfarction (OR = 1.16; 95% CI, 0.58–2.30), cardiogenic shock (OR = 1.51; 95% CI, 0.74–3.08), stroke (OR = 2.30; 95% CI, 0.29–17.99), and overall mortality (OR = 1.16; 95% CI = 0.74–1.83) were independent predictive factors for first presentation AMI. CONCLUSIONS: First presentation AMI patients tend to be older and to have lower rates of risk factors. Adverse clinical outcomes such as congestive heart failure, reinfarction, cardiogenic shock, and stroke were higher among patients with first presentation AMI compared to patients with a history of ACS.
format Online
Article
Text
id pubmed-6026399
institution National Center for Biotechnology Information
language English
publishDate 2018
publisher Elsevier
record_format MEDLINE/PubMed
spelling pubmed-60263992018-07-06 Baseline characteristics, management practices, and long-term outcomes among patients with first presentation acute myocardial infarction in the Second Gulf Registry of Acute Coronary Events (Gulf RACE-II) Joury, Abdulaziz U. Hersi, Ahmed S. Alfaleh, Hussam Alhabib, Khalid F. Kashour, Tarek Seifaw J Saudi Heart Assoc Original Article BACKGROUND AND OBJECTIVES: Limited data are available highlighting the different clinical aspects of acute coronary syndrome (ACS) patients, especially in Gulf countries. In this study, we aimed to compare patients who presented with acute myocardial infarction (AMI) as the first presentation of patients who have a history of ACS in terms of initial presentation, medical history, laboratory findings, and overall mortality. METHODS: We used the Second Gulf Registry of Acute Coronary Events (Gulf RACE-II), which is a multinational observational study of 7930 ACS patients. RESULTS: Among all patients, 4723 (59.6%) patients presented with AMI. First presentation AMI patients were older (mean age, 55 years vs. 53 years; p < 0.001) and had lower risk factors than patients with a history of ACS. Higher laboratory readings of cardiac markers and all aspects of mortality were significantly higher among patients with first presentation AMI. After adjustments for baseline variables, congestive heart failure [odds ratio (OR) = 1.08; 95% confidence interval (CI), 0.73–1.57], reinfarction (OR = 1.16; 95% CI, 0.58–2.30), cardiogenic shock (OR = 1.51; 95% CI, 0.74–3.08), stroke (OR = 2.30; 95% CI, 0.29–17.99), and overall mortality (OR = 1.16; 95% CI = 0.74–1.83) were independent predictive factors for first presentation AMI. CONCLUSIONS: First presentation AMI patients tend to be older and to have lower rates of risk factors. Adverse clinical outcomes such as congestive heart failure, reinfarction, cardiogenic shock, and stroke were higher among patients with first presentation AMI compared to patients with a history of ACS. Elsevier 2018-07 2018-03-17 /pmc/articles/PMC6026399/ /pubmed/29983497 http://dx.doi.org/10.1016/j.jsha.2018.03.001 Text en © 2018 The Authors http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Original Article
Joury, Abdulaziz U.
Hersi, Ahmed S.
Alfaleh, Hussam
Alhabib, Khalid F.
Kashour, Tarek Seifaw
Baseline characteristics, management practices, and long-term outcomes among patients with first presentation acute myocardial infarction in the Second Gulf Registry of Acute Coronary Events (Gulf RACE-II)
title Baseline characteristics, management practices, and long-term outcomes among patients with first presentation acute myocardial infarction in the Second Gulf Registry of Acute Coronary Events (Gulf RACE-II)
title_full Baseline characteristics, management practices, and long-term outcomes among patients with first presentation acute myocardial infarction in the Second Gulf Registry of Acute Coronary Events (Gulf RACE-II)
title_fullStr Baseline characteristics, management practices, and long-term outcomes among patients with first presentation acute myocardial infarction in the Second Gulf Registry of Acute Coronary Events (Gulf RACE-II)
title_full_unstemmed Baseline characteristics, management practices, and long-term outcomes among patients with first presentation acute myocardial infarction in the Second Gulf Registry of Acute Coronary Events (Gulf RACE-II)
title_short Baseline characteristics, management practices, and long-term outcomes among patients with first presentation acute myocardial infarction in the Second Gulf Registry of Acute Coronary Events (Gulf RACE-II)
title_sort baseline characteristics, management practices, and long-term outcomes among patients with first presentation acute myocardial infarction in the second gulf registry of acute coronary events (gulf race-ii)
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6026399/
https://www.ncbi.nlm.nih.gov/pubmed/29983497
http://dx.doi.org/10.1016/j.jsha.2018.03.001
work_keys_str_mv AT jouryabdulazizu baselinecharacteristicsmanagementpracticesandlongtermoutcomesamongpatientswithfirstpresentationacutemyocardialinfarctioninthesecondgulfregistryofacutecoronaryeventsgulfraceii
AT hersiahmeds baselinecharacteristicsmanagementpracticesandlongtermoutcomesamongpatientswithfirstpresentationacutemyocardialinfarctioninthesecondgulfregistryofacutecoronaryeventsgulfraceii
AT alfalehhussam baselinecharacteristicsmanagementpracticesandlongtermoutcomesamongpatientswithfirstpresentationacutemyocardialinfarctioninthesecondgulfregistryofacutecoronaryeventsgulfraceii
AT alhabibkhalidf baselinecharacteristicsmanagementpracticesandlongtermoutcomesamongpatientswithfirstpresentationacutemyocardialinfarctioninthesecondgulfregistryofacutecoronaryeventsgulfraceii
AT kashourtarekseifaw baselinecharacteristicsmanagementpracticesandlongtermoutcomesamongpatientswithfirstpresentationacutemyocardialinfarctioninthesecondgulfregistryofacutecoronaryeventsgulfraceii
AT baselinecharacteristicsmanagementpracticesandlongtermoutcomesamongpatientswithfirstpresentationacutemyocardialinfarctioninthesecondgulfregistryofacutecoronaryeventsgulfraceii