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Serum cholesterol levels and tumor growth in a PTEN-null transgenic mouse model of prostate cancer

BACKGROUND: Some, but not all, epidemiologic evidence supports a role for cholesterol, the precursor for steroid hormone synthesis, in prostate cancer. Using a PTEN-null transgenic mouse model of prostate cancer, we tested the effect of modifying serum cholesterol levels on prostate tumor developmen...

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Detalles Bibliográficos
Autores principales:	Allott, Emma H., Masko, Elizabeth M., Freedland, Alexis R., Macias, Everardo, Pelton, Kristine, Solomon, Keith R., Mostaghel, Elahe A., Thomas, George V., Pizzo, Salvatore V., Freeman, Michael R., Freedland, Stephen J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6026483/ https://www.ncbi.nlm.nih.gov/pubmed/29795142 http://dx.doi.org/10.1038/s41391-018-0045-x

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