Modulation of Amyloidogenesis Controlled by the C-Terminal Domain of Islet Amyloid Polypeptide Shows New Functions on Hepatocyte Cholesterol Metabolism

The islet amyloid polypeptide (IAPP) or amylin maintains a key role in metabolism. This 37-residues-peptide could form pancreatic amyloids, which are a characteristic feature of diabetes mellitus type 2. However, some species do not form amyloid fibril structures. By employing a biomimetic approach,...

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Detalles Bibliográficos
Autores principales: Pulido-Capiz, Angel, Díaz-Molina, Raúl, Martínez-Navarro, Israel, Guevara-Olaya, Lizbeth A., Casanueva-Pérez, Enrique, Mas-Oliva, Jaime, Rivero, Ignacio A., García-González, Victor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Endocrinology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6026639/
https://www.ncbi.nlm.nih.gov/pubmed/29988450
http://dx.doi.org/10.3389/fendo.2018.00331

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