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Lipopolysaccharide-Induced Dephosphorylation of AMPK-Activated Protein Kinase Potentiates Inflammatory Injury via Repression of ULK1-Dependent Autophagy
AMP-activated protein kinase (AMPK) is a crucial metabolic regulator with profound modulatory activities on inflammation. Although the anti-inflammatory benefits of AMPK activators were well documented in experimental studies, the pathological significance of endogenous AMPK in inflammatory disorder...
Autores principales: | Fan, Kerui, Lin, Ling, Ai, Qing, Wan, Jingyuan, Dai, Jie, Liu, Gang, Tang, Li, Yang, Yongqiang, Ge, Pu, Jiang, Rong, Zhang, Li |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6026648/ https://www.ncbi.nlm.nih.gov/pubmed/29988556 http://dx.doi.org/10.3389/fimmu.2018.01464 |
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