Modeling Hemolytic-Uremic Syndrome: In-Depth Characterization of Distinct Murine Models Reflecting Different Features of Human Disease

Diarrhea-positive hemolytic-uremic syndrome (HUS) is a renal disorder that results from infections with Shiga-toxin (Stx)-producing Escherichia coli. The aim of this study was to establish well-defined refined murine models of HUS that can serve as preclinical tools to elucidate molecular mechanisms...

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Detalles Bibliográficos
Autores principales: Dennhardt, Sophie, Pirschel, Wiebke, Wissuwa, Bianka, Daniel, Christoph, Gunzer, Florian, Lindig, Sandro, Medyukhina, Anna, Kiehntopf, Michael, Rudolph, Wolfram W., Zipfel, Peter F., Gunzer, Matthias, Figge, Marc Thilo, Amann, Kerstin, Coldewey, Sina M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6026657/
https://www.ncbi.nlm.nih.gov/pubmed/29988557
http://dx.doi.org/10.3389/fimmu.2018.01459

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