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Vav1 downmodulates Akt in different breast cancer subtypes: a new promising chance to improve breast cancer outcome

Targeting different members of the Akt pathways is a promising therapeutic chance in solid tumors including breast cancer. The variable expression levels of Akt isoforms with opposite effects on tumor growth and metastasis, however, make it difficult to select the inhibitors to be used for specific...

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Detalles Bibliográficos
Autores principales:	Grassilli, Silvia, Brugnoli, Federica, Lattanzio, Rossano, Marchisio, Marco, Perracchio, Letizia, Piantelli, Mauro, Bavelloni, Alberto, Capitani, Silvano, Bertagnolo, Valeria
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2018
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6026867/ https://www.ncbi.nlm.nih.gov/pubmed/29658179 http://dx.doi.org/10.1002/1878-0261.12203

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