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Amyloid-β, Tau, and Cognition in Cognitively Normal Older Individuals: Examining the Necessity to Adjust for Biomarker Status in Normative Data

We investigated whether amyloid-β (Aβ) and tau affected cognition in cognitively normal (CN) individuals, and whether norms for neuropsychological tests based on biomarker-negative individuals would improve early detection of dementia. We included 907 CN individuals from 8 European cohorts and from...

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Detalles Bibliográficos
Autores principales: Bos, Isabelle, Vos, Stephanie J. B., Jansen, Willemijn J., Vandenberghe, Rik, Gabel, Silvy, Estanga, Ainara, Ecay-Torres, Mirian, Tomassen, Jori, den Braber, Anouk, Lleó, Alberto, Sala, Isabel, Wallin, Anders, Kettunen, Petronella, Molinuevo, José L., Rami, Lorena, Chetelat, Gaël, de la Sayette, Vincent, Tsolaki, Magda, Freund-Levi, Yvonne, Johannsen, Peter, Novak, Gerald P., Ramakers, Inez, Verhey, Frans R., Visser, Pieter Jelle
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6027060/
https://www.ncbi.nlm.nih.gov/pubmed/29988624
http://dx.doi.org/10.3389/fnagi.2018.00193