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Nose-to-Brain Delivery of Antiviral Drugs: A Way to Overcome Their Active Efflux?
Although several viruses can easily infect the central nervous system (CNS), antiviral drugs often show dramatic difficulties in penetrating the brain from the bloodstream since they are substrates of active efflux transporters (AETs). These transporters, located in the physiological barriers betwee...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2018
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6027266/ https://www.ncbi.nlm.nih.gov/pubmed/29587409 http://dx.doi.org/10.3390/pharmaceutics10020039 |