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Strengths and Weaknesses of the Current Strategies to Map and Characterize R-Loops
R-loops are evolutionarily conserved three-stranded structures that result from the formation of stable DNA:RNA hybrids in the genome. R-loops have attracted increasing interest in recent years as potent regulators of gene expression and genome stability. In particular, their strong association with...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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MDPI
2018
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6027298/ https://www.ncbi.nlm.nih.gov/pubmed/29657305 http://dx.doi.org/10.3390/ncrna4020009 |