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Strengths and Weaknesses of the Current Strategies to Map and Characterize R-Loops

R-loops are evolutionarily conserved three-stranded structures that result from the formation of stable DNA:RNA hybrids in the genome. R-loops have attracted increasing interest in recent years as potent regulators of gene expression and genome stability. In particular, their strong association with...

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Detalles Bibliográficos
Autor principal: Vanoosthuyse, Vincent
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6027298/
https://www.ncbi.nlm.nih.gov/pubmed/29657305
http://dx.doi.org/10.3390/ncrna4020009

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