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Requirement of the Dynein-Adaptor Spindly for Mitotic and Post-Mitotic Functions in Drosophila

Spindly was originally identified as a specific regulator of Dynein activity at the kinetochore. In early prometaphase, Spindly recruits the Dynein/Dynactin complex, promoting the establishment of stable kinetochore-microtubule interactions and progression into anaphase. While details of Spindly fun...

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Detalles Bibliográficos
Autores principales: Clemente, Giuliana D., Hannaford, Matthew R., Beati, Hamze, Kapp, Katja, Januschke, Jens, Griffis, Eric R., Müller, Hans-Arno J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6027351/
https://www.ncbi.nlm.nih.gov/pubmed/29615558
http://dx.doi.org/10.3390/jdb6020009