A Miniaturized Extruder to Prototype Amorphous Solid Dispersions: Selection of Plasticizers for Hot Melt Extrusion

Hot-melt extrusion is an option to fabricate amorphous solid dispersions and to enhance oral bioavailability of poorly soluble compounds. The selection of suitable polymer carriers and processing aids determines the dissolution, homogeneity and stability performance of this solid dosage form. A mini...

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Detalles Bibliográficos
Autores principales: Lauer, Matthias E., Maurer, Reto, De Paepe, Anne T., Stillhart, Cordula, Jacob, Laurence, James, Rajesh, Kojima, Yuki, Rietmann, Rene, Kissling, Tom, van den Ende, Joost A., Schwarz, Sabine, Grassmann, Olaf, Page, Susanne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6027370/
https://www.ncbi.nlm.nih.gov/pubmed/29783755
http://dx.doi.org/10.3390/pharmaceutics10020058

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6027370/
https://www.ncbi.nlm.nih.gov/pubmed/29783755
http://dx.doi.org/10.3390/pharmaceutics10020058

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