LHX2 Mediates the FGF-to-SHH Regulatory Loop during Limb Development

During limb development, fibroblast growth factors (Fgfs) govern proximal–distal outgrowth and patterning. FGFs also synchronize developmental patterning between the proximal–distal and anterior–posterior axes by maintaining Sonic hedgehog (Shh) expression in cells of the zone of polarizing activity...

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Detalles Bibliográficos
Autores principales: Watson, Billy A., Feenstra, Jennifer M., Van Arsdale, Jonathan M., Rai-Bhatti, Karndeep S., Kim, Diana J. H., Coggins, Ashley S., Mattison, Gennaya L., Yoo, Stephen, Steinman, Eric D., Pira, Charmaine U., Gongol, Brendan R., Oberg, Kerby C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6027391/
https://www.ncbi.nlm.nih.gov/pubmed/29914077
http://dx.doi.org/10.3390/jdb6020013

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