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LHX2 Mediates the FGF-to-SHH Regulatory Loop during Limb Development
During limb development, fibroblast growth factors (Fgfs) govern proximal–distal outgrowth and patterning. FGFs also synchronize developmental patterning between the proximal–distal and anterior–posterior axes by maintaining Sonic hedgehog (Shh) expression in cells of the zone of polarizing activity...
Autores principales: | Watson, Billy A., Feenstra, Jennifer M., Van Arsdale, Jonathan M., Rai-Bhatti, Karndeep S., Kim, Diana J. H., Coggins, Ashley S., Mattison, Gennaya L., Yoo, Stephen, Steinman, Eric D., Pira, Charmaine U., Gongol, Brendan R., Oberg, Kerby C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6027391/ https://www.ncbi.nlm.nih.gov/pubmed/29914077 http://dx.doi.org/10.3390/jdb6020013 |
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