Cargando…

Roadmap for Investigating Epigenome Deregulation and Environmental Origins of Cancer

The interaction between the (epi)genetic makeup of an individual and his/her environmental exposure record (exposome) is accepted as a determinant factor for a significant proportion of human malignancies. Recent evidence has highlighted the key role of epigenetic mechanisms in mediating gene–enviro...

Descripción completa

Detalles Bibliográficos
Autores principales:	Herceg, Zdenko, Ghantous, Akram, Wild, Christopher P., Sklias, Athena, Casati, Lavinia, Duthie, Susan J., Fry, Rebecca, Issa, Jean-Pierre, Kellermayer, Richard, Koturbash, Igor, Kondo, Yukata, Lepeule, Johanna, Lima, Sheila C.S., Marsit, Carmen J, Rakyan, Vardhman, Saffery, Richard, Taylor, Jack A., Teschendorff, Andrew E., Ushijima, Toshikazu, Vineis, Paolo, Walker, Cheryl Lyn, Waterland, Robert A., Wiemels, Joe, Ambatipudi, Srikant, Esposti, Davide Degli, Hernandez-Vargas, Hector
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6027626/ https://www.ncbi.nlm.nih.gov/pubmed/28836271 http://dx.doi.org/10.1002/ijc.31014

Ejemplares similares

Aberrant DNA methylation of imprinted loci in hepatocellular carcinoma and after in vitro exposure to common risk factors
por: Lambert, Marie-Pierre, et al.
Publicado: (2015)

Targeted deep sequencing of plasma circulating cell-free DNA reveals Vimentin and Fibulin 1 as potential epigenetic biomarkers for hepatocellular carcinoma
por: Holmila, Reetta, et al.
Publicado: (2017)

Optimized DNA extraction from neonatal dried blood spots: application in methylome profiling
por: Ghantous, Akram, et al.
Publicado: (2014)

The hunt for mammalian epialleles
por: Rakyan, Vardhman
Publicado: (2012)

Identifying and correcting epigenetics measurements for systematic sources of variation
por: Perrier, Flavie, et al.
Publicado: (2018)

Genome-wide DNA methylation analysis for diabetic nephropathy in type 1 diabetes mellitus
por: Bell, Christopher G, et al.
Publicado: (2010)

Correcting for cell-type composition bias in epigenome-wide association studies
por: Lowe, Robert, et al.
Publicado: (2014)

Marmal-aid – a database for Infinium HumanMethylation450
por: Lowe, Robert, et al.
Publicado: (2013)

Unique DNA methylation signature in HPV-positive head and neck squamous cell carcinomas
por: Degli Esposti, Davide, et al.
Publicado: (2017)

miR-500a-5p regulates oxidative stress response genes in breast cancer and predicts cancer survival
por: Degli Esposti, Davide, et al.
Publicado: (2017)

Histone deacetylase inhibitors potentiate photodynamic therapy in colon cancer cells marked by chromatin-mediated epigenetic regulation of CDKN1A
por: Halaburková, Andrea, et al.
Publicado: (2017)

A community-based cross-sectional survey of orthostatic hypotension among elderly from south India
por: Sasidharan, Akhil, et al.
Publicado: (2022)

BulkVis: a graphical viewer for Oxford nanopore bulk FAST5 files
por: Payne, Alexander, et al.
Publicado: (2019)

DNA methylation of insulin-like growth factor 2 and H19 cluster in cord blood and prenatal air pollution exposure to fine particulate matter
por: Wang, Congrong, et al.
Publicado: (2020)

Interrelationships and determinants of aging biomarkers in cord blood
por: Reimann, Brigitte, et al.
Publicado: (2022)

Prognostic Classifier Based on Genome-Wide DNA Methylation Profiling in Well-Differentiated Thyroid Tumors
por: Bisarro dos Reis, Mariana, et al.
Publicado: (2017)

Integrated data analysis reveals potential drivers and pathways disrupted by DNA methylation in papillary thyroid carcinomas
por: Beltrami, Caroline Moraes, et al.
Publicado: (2017)

The human blood DNA methylome displays a highly distinctive profile compared with other somatic tissues
por: Lowe, Robert, et al.
Publicado: (2015)

Correlation of an epigenetic mitotic clock with cancer risk
por: Yang, Zhen, et al.
Publicado: (2016)

Sexually dimorphic gene expression emerges with embryonic genome activation and is dynamic throughout development
por: Lowe, Robert, et al.
Publicado: (2015)

Placenta-specific Methylation of the Vitamin D 24-Hydroxylase Gene: IMPLICATIONS FOR FEEDBACK AUTOREGULATION OF ACTIVE VITAMIN D LEVELS AT THE FETOMATERNAL INTERFACE
por: Novakovic, Boris, et al.
Publicado: (2009)

Socioeconomic position during pregnancy and DNA methylation signatures at three stages across early life: epigenome-wide association studies in the ALSPAC birth cohort
por: Alfano, Rossella, et al.
Publicado: (2019)

Epigenetic remodelling of enhancers in response to estrogen deprivation and re-stimulation
por: Sklias, Athena, et al.
Publicado: (2021)

Identification of novel long non-coding RNAs deregulated in hepatocellular carcinoma using RNA-sequencing
por: Esposti, Davide Degli, et al.
Publicado: (2016)

Pan-cancer multi-omics analysis and orthogonal experimental assessment of epigenetic driver genes
por: Halaburkova, Andrea, et al.
Publicado: (2020)

DNA Methylation-mediated Down-regulation of DNA Methyltransferase-1 (DNMT1) Is Coincident with, but Not Essential for, Global Hypomethylation in Human Placenta
por: Novakovic, Boris, et al.
Publicado: (2010)

A functional methylome map of ulcerative colitis
por: Häsler, Robert, et al.
Publicado: (2012)

Blood DNA methylation and breast cancer risk: a meta-analysis of four prospective cohort studies
por: Bodelon, Clara, et al.
Publicado: (2019)

Early life diet conditions the molecular response to post-weaning protein restriction in the mouse
por: Danson, Amy F., et al.
Publicado: (2018)

From hepatitis to hepatocellular carcinoma: a proposed model for cross-talk between inflammation and epigenetic mechanisms
por: Martin, Marion, et al.
Publicado: (2012)

DNA Methylation in Inflammatory Pathways Modifies the Association between BMI and Adult-Onset Non-Atopic Asthma
por: Jeong, Ayoung, et al.
Publicado: (2019)

Clinical outcomes and health care costs combining metformin with sitagliptin or sulphonylureas or thiazolidinediones in uncontrolled type 2 diabetes patients
por: Degli Esposti, Luca, et al.
Publicado: (2014)

Drug adherence to olmesartan/amlodipine fixed combination in an Italian clinical practice setting
por: Degli Esposti, Luca, et al.
Publicado: (2014)

The Cord Blood Insulin and Mitochondrial DNA Content Related Methylome
por: Reimann, Brigitte, et al.
Publicado: (2019)

Bcl-2 antagonists and cancer: from the clinic, back to the bench
por: Esposti, M Degli
Publicado: (2010)

Genome Analysis of Structure–Function Relationships in Respiratory Complex I, an Ancient Bioenergetic Enzyme
por: Degli Esposti, Mauro
Publicado: (2015)

Bioenergetic Evolution in Proteobacteria and Mitochondria
por: Degli Esposti, Mauro
Publicado: (2014)

A Journey across Genomes Uncovers the Origin of Ubiquinone in Cyanobacteria
por: Degli Esposti, Mauro
Publicado: (2017)

Late Mitochondrial Acquisition, Really?
por: Degli Esposti, Mauro
Publicado: (2016)

Methylation-based markers of aging and lifestyle-related factors and risk of breast cancer: a pooled analysis of four prospective studies
por: Dugué, Pierre-Antoine, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_ful9h7kiocpperp26176vos0nn