Novel Mutations in pncA Gene of Pyrazinamide Resistant Clinical Isolates of Mycobacterium tuberculosis

In clinical isolates of Mycobacterium tuberculosis (MTB), resistance to pyrazinamide occurs by mutations in any positions of the pncA gene (NC_000962.3) especially in nucleotides 359 and 374. In this study we examined the pncA gene sequence in clinical isolates of MTB. Genomic DNA of 33 clinical iso...

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Detalles Bibliográficos
Autores principales: Kahbazi, Manijeh, Sarmadian, Hossein, Ahmadi, Azam, Didgar, Farshideh, Sadrnia, Maryam, Poolad, Toktam, Arjomandzadegan, Mohammad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6027673/
https://www.ncbi.nlm.nih.gov/pubmed/29659533
http://dx.doi.org/10.3390/scipharm86020015

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6027673/
https://www.ncbi.nlm.nih.gov/pubmed/29659533
http://dx.doi.org/10.3390/scipharm86020015

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