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Novel Mutations in pncA Gene of Pyrazinamide Resistant Clinical Isolates of Mycobacterium tuberculosis
In clinical isolates of Mycobacterium tuberculosis (MTB), resistance to pyrazinamide occurs by mutations in any positions of the pncA gene (NC_000962.3) especially in nucleotides 359 and 374. In this study we examined the pncA gene sequence in clinical isolates of MTB. Genomic DNA of 33 clinical iso...
Autores principales: | Kahbazi, Manijeh, Sarmadian, Hossein, Ahmadi, Azam, Didgar, Farshideh, Sadrnia, Maryam, Poolad, Toktam, Arjomandzadegan, Mohammad |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6027673/ https://www.ncbi.nlm.nih.gov/pubmed/29659533 http://dx.doi.org/10.3390/scipharm86020015 |
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