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The direct and indirect effects of α-synuclein on microtubule stability in the pathogenesis of Parkinson’s disease

Despite decades of research, the mechanism of Parkinson’s disease pathogenesis remains unclear. Studies have focused heavily on the protein α-synuclein, which is the primary component of Lewy bodies, the pathologic inclusions that are the hallmark of Parkinson’s on the cellular level. While the role...

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Detalles Bibliográficos
Autores principales: Carnwath, Tom, Mohammed, Raihan, Tsiang, Daniel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6027679/
https://www.ncbi.nlm.nih.gov/pubmed/29983568
http://dx.doi.org/10.2147/NDT.S166322