Cargando…

Quantification of 6-Mercaptopurine and Its Metabolites in Patients with Acute Lympoblastic Leukemia Using Dried Blood Spots and UPLC-MS/MS

This research aimed to quantitatively bioanalyze 6-mercaptopurine (6-MP), 6-methylmercaptopurine (6-MMP), and 6-thioguanosine-5′-monophosphate (6-TGMP) in dried blood spots (DBS) prepared from a small volume of acute lymphoblastic leukemia (ALL) patients. Analytes on the DBS card were extracted usin...

Descripción completa

Detalles Bibliográficos
Autores principales:	Supandi, Supandi, Harahap, Yahdiana, Harmita, Harmita, Andalusia, Rizka
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6027686/ https://www.ncbi.nlm.nih.gov/pubmed/29693618 http://dx.doi.org/10.3390/scipharm86020018

Ejemplares similares

Analysis of tamoxifen and its metabolites in dried blood spot and volumetric absorptive microsampling: comparison and clinical application
por: Maggadani, Baitha Palanggatan, et al.
Publicado: (2021)

Determination of Ethinyl Estradiol and Levonorgestrel in Human Plasma with Prednisone as Internal Standard Using Ultra-performance Liquid Chromatography–Tandem Mass Spectrometry
por: Harahap, Yahdiana, et al.
Publicado: (2019)

Quantification of Zonisamide in Dried Blood Spots and Dried Plasma Spots by UPLC–MS/MS: Application to Clinical Practice
por: Rmandić, Milena, et al.
Publicado: (2022)

Development and validation of a UPLC-MS/MS method with volumetric absorptive microsampling to quantitate cyclophosphamide and 4-hydroxycyclophosphamide
por: Harahap, Yahdiana, et al.
Publicado: (2022)

Volumetric Absorptive Microsampling as a New Biosampling Tool for Monitoring of Tamoxifen, Endoxifen, 4-OH Tamoxifen and N-Desmethyltamoxifen in Breast Cancer Patients
por: Maggadani, Baitha Palanggatan, et al.
Publicado: (2021)

Development and Validation of Doxorubicin Hydrochloride and Doxorubicinol Quantification Method in Dried Blood Spot by Liquid Chromatography–Tandem Mass Spectrometry
por: Harahap, Yahdiana, et al.
Publicado: (2020)

Vertical Transfer of Metabolites Detectable from Newborn’s Dried Blood Spot Samples Using UPLC-MS: A Chemometric Study
por: Olarini, Alessandra, et al.
Publicado: (2022)

Development, validation, and clinical application of an FIA‐MS/MS method for the quantification of lysophosphatidylcholines in dried blood spots
por: Yue, Xiaofei, et al.
Publicado: (2021)

UPLC-ESI-MRM/MS for Absolute Quantification and MS/MS Structural Elucidation of Six Specialized Pyranonaphthoquinone Metabolites From Ventilago harmandiana
por: Limjiasahapong, Suphitcha, et al.
Publicado: (2021)

A New Method to Quantify Ifosfamide Blood Levels Using Dried Blood Spots and UPLC-MS/MS in Paediatric Patients with Embryonic Solid Tumours
por: Torres, Luz-María, et al.
Publicado: (2015)

Quantification of Lappaconitine in Mouse Blood by UPLC-MS/MS and Its Application to a Pharmacokinetic Study
por: Chen, Fan, et al.
Publicado: (2019)

Analysis of Flavonoid Metabolites in Buckwheat Leaves Using UPLC-ESI-MS/MS
por: Li, Jing, et al.
Publicado: (2019)

Analysis of Flavonoid Metabolites in Chaenomeles Petals Using UPLC-ESI-MS/MS
por: Shen, Ting, et al.
Publicado: (2020)

Quantitation of mycophenolic acid and metabolites by UPLC-MS/MS in renal transplant patients
por: Huang, Yun-Fen, et al.
Publicado: (2022)

Identification of Sanguinarine Metabolites in Rats Using UPLC-Q-TOF-MS/MS
por: Liu, Mengting, et al.
Publicado: (2023)

Pharmacokinetic and Metabolism Studies of Curculigoside C by UPLC-MS/MS and UPLC-QTOF-MS
por: Wu, Di, et al.
Publicado: (2018)

Validation data for the quantification of the Annonaceous acetogenin annonacin in Rat brain by UPLC-MS/MS
por: Bonneau, Natacha, et al.
Publicado: (2016)

Quantification of twenty pharmacologically active dyes in water samples using UPLC-MS/MS
por: Tkaczyk-Wlizło, Angelika, et al.
Publicado: (2022)

Quantification of Venetoclax for Therapeutic Drug Monitoring in Chinese Acute Myeloid Leukemia Patients by a Validated UPLC-MS/MS Method
por: Yang, Xi, et al.
Publicado: (2022)

UPLC-MS/MS Method for Simultaneous Determination of Three Major Metabolites of Mequindox in Holothurian
por: Liu, Huihui, et al.
Publicado: (2018)

Effects of Dexmedetomidine on the Pharmacokinetics of Parecoxib and Its Metabolite Valdecoxib in Beagles by UPLC-MS/MS
por: Hu, Jie, et al.
Publicado: (2020)

Metabolite Profiling and Distribution of Militarine in Rats Using UPLC-Q-TOF-MS/MS
por: Li, Limin, et al.
Publicado: (2020)

An UPLC-MS/MS Method for Simultaneous Quantification of the Components of Shenyanyihao Oral Solution in Rat Plasma
por: Jiang, Chunbo, et al.
Publicado: (2020)

Pharmacokinetics and UPLC-MS/MS of Delsoline in Mouse Whole Blood
por: Shao, Lingjiu, et al.
Publicado: (2018)

Analysis of Acrylamide in Dried Blood Spots of Lung Cancer Patients by Ultrahigh-Performance Liquid Chromatography Tandem Mass Spectrometry
por: Harahap, Yahdiana, et al.
Publicado: (2020)

Metabolite profile of COVID-19 revealed by UPLC-MS/MS-based widely targeted metabolomics
por: Liu, Jun, et al.
Publicado: (2022)

Identification of Acid Hydrolysis Metabolites of the Pimelea Toxin Simplexin for Targeted UPLC-MS/MS Analysis
por: Loh, Zhi Hung, et al.
Publicado: (2023)

Quantification of cobimetinib, cabozantinib, dabrafenib, niraparib, olaparib, vemurafenib, regorafenib and its metabolite regorafenib M2 in human plasma by UPLC–MS/MS
por: Krens, Stefanie D., et al.
Publicado: (2020)

Metabolite Profiling of 14 Wuyi Rock Tea Cultivars Using UPLC-QTOF MS and UPLC-QqQ MS Combined with Chemometrics
por: Chen, Si, et al.
Publicado: (2018)

Method Development and Validation for Measuring O(6)-Methylguanine in Dried Blood Spot Using Ultra High-Performance Liquid Chromatography Tandem Mass Spectrometry
por: Harahap, Yahdiana, et al.
Publicado: (2021)

Pharmacokinetic and Metabolism Studies of 12-Riboside-Pseudoginsengenin DQ by UPLC-MS/MS and UPLC-QTOF-MS(E)
por: Wang, Zhenzhou, et al.
Publicado: (2018)

Validated UPLC-MS/MS method for quantification of fruquintinib in rat plasma and its application to pharmacokinetic study
por: Mei, Yi-Bin, et al.
Publicado: (2019)

Highly sensitive quantification of pemetrexed in human plasma using UPLC‐MS/MS to support microdosing studies
por: van Ewijk‐Beneken Kolmer, Eleonora W. J., et al.
Publicado: (2021)

Development, validation and clinical application of a method for the simultaneous quantification of lamivudine, emtricitabine and tenofovir in dried blood and dried breast milk spots using LC–MS/MS
por: Waitt, Catriona, et al.
Publicado: (2017)

A selective detection of lysophosphatidylcholine in dried blood spots for diagnosis of adrenoleukodystrophy by LC-MS/MS
por: Mashima, Ryuichi, et al.
Publicado: (2016)

Analysis of Flavonoid Metabolites in Citrus Peels (Citrus reticulata “Dahongpao”) Using UPLC-ESI-MS/MS
por: Wang, Fu, et al.
Publicado: (2019)

New UPLC–MS/MS assay for the determination of tamoxifen and its metabolites in human plasma, application to patients
por: Bobin-Dubigeon, Christine, et al.
Publicado: (2019)

Effects of Dexmedetomidine on the Pharmacokinetics of Dezocine, Midazolam and Its Metabolite 1-Hydroxymidazolam in Beagles by UPLC-MS/MS
por: Zhou, Wei, et al.
Publicado: (2020)

Osteoprotective Activity and Metabolite Fingerprint via UPLC/MS and GC/MS of Lepidium sativum in Ovariectomized Rats
por: Abdallah, Hossam M., et al.
Publicado: (2020)

A UPLC-MS/MS application for comparisons of the hepatotoxicity of raw and processed Xanthii Fructus by energy metabolites
por: Jiang, Hai, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_2q1pul8geo39odaj6uae04s9u2