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Confidence and Prediction Intervals for Pharmacometric Models
Supporting decision making in drug development is a key purpose of pharmacometric models. Pharmacokinetic models predict exposures under alternative posologies or in different populations. Pharmacodynamic models predict drug effects based on exposure to drug, disease, or other patient characteristic...
Autores principales: | Kümmel, Anne, Bonate, Peter L., Dingemanse, Jasper, Krause, Andreas |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6027739/ https://www.ncbi.nlm.nih.gov/pubmed/29388347 http://dx.doi.org/10.1002/psp4.12286 |
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